ABCE1 and RNASE2

Data Source:
HPRD (in vitro, in vivo)

		ABCE1	RNASE2
Description		ATP binding cassette subfamily E member 1	ribonuclease A family member 2
Image
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol Eukaryotic Translation Initiation Factor 3 Complex Membrane	Extracellular Region Extracellular Space Azurophil Granule Lumen Extracellular Exosome
	Molecular Function	Iron Ion Binding Protein Binding ATP Binding ATPase Activity Ribosomal Small Subunit Binding Endoribonuclease Inhibitor Activity	Lipopolysaccharide Binding Nucleic Acid Binding Ribonuclease A Activity Ribonuclease Activity Protein Binding Lyase Activity
	Biological Process	Ribosomal Subunit Export From Nucleus Translational Initiation Translational Termination Viral Process Defense Response To Virus Regulation Of Type I Interferon-mediated Signaling Pathway Negative Regulation Of Endoribonuclease Activity	Innate Immune Response In Mucosa RNA Catabolic Process Chemotaxis Induction Of Bacterial Agglutination Neutrophil Degranulation Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium Defense Response To Virus RNA Phosphodiester Bond Hydrolysis RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways		OAS antiviral response Interferon alpha/beta signaling	Neutrophil degranulation
Drugs			Adenosine 3',5'-diphosphate Adenosine-2'-5'-Diphosphate
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Malaria ( 31844061) Subcortical volume (MOSTest) ( 32665545) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Blood protein levels ( 30072576 29875488) Crohn's disease ( 20570966)
Interacting Genes		3 interacting genes: EIF3J RNASE2 RNASEL	3 interacting genes: ABCE1 DLG2 YWHAQ
Entrez ID		6059	6036
HPRD ID		03132	00577
Ensembl ID		ENSG00000164163	ENSG00000169385
Uniprot IDs		P61221	P10153 W0UV60
PDB IDs		6ZME 6ZVJ 7A09	1GQV 1HI2 1HI3 1HI4 1HI5 1K2A 2BEX 2BZZ 2C01 2C02 2C05 5E13
Enriched GO Terms of Interacting Partners?
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