EIF3J and MAGED1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		EIF3J	MAGED1
Description		eukaryotic translation initiation factor 3 subunit J	MAGE family member D1
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Eukaryotic Translation Initiation Factor 3 Complex Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex	Chromatin Nucleus Cytoplasm Plasma Membrane Protein-containing Complex
	Molecular Function	Translation Initiation Factor Activity Protein Binding Identical Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Formation Of Cytoplasmic Translation Initiation Complex Translational Initiation	Regulation Of Transcription, DNA-templated Circadian Regulation Of Gene Expression Regulation Of Apoptotic Process Negative Regulation Of Epithelial Cell Proliferation
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit	NRAGE signals death through JNK Caspase activation via Dependence Receptors in the absence of ligand
Drugs
Diseases
GWAS		Anti-Toxoplasma gondii IgG seropositivity ( 30610941)
Interacting Genes		15 interacting genes: ABCE1 CASP3 CSNK2A1 EIF3A EIF3B EIF3C EIF3D EIF3K GNB5 GOLM1 MAGED1 METTL3 SIAH1 TADA3 TPD52L1	125 interacting genes: AGRN AKAP9 ARHGEF16 ARID5A ARNT2 BAG3 BAG4 BARD1 BHLHE40 BIRC8 BRCA2 C1orf94 CA8 CAPN7 CCDC120 CCDC33 CDC23 CERCAM CFAP206 CHERP DAB1 DAZAP2 DDX6 DLX4 DLX5 DMRT2 EIF3J EIF4E2 EP300 ERCC3 FAM83A FOXD2 FOXH1 FOXI1 GATA5 GLRA1 GLYCTK GPANK1 GPR135 GRAP2 HEMK1 HGS HIVEP1 HNRNPH1 HNRNPLL HOXC9 HSF2BP KPNA2 KPNA6 KRTAP19-5 KRTAP6-1 KRTAP6-3 LARP4B LENG8 LONRF1 MAPK1IP1L MAPK3 MDFI MEOX2 MGAT5B MKRN3 MPC1 MSX2 NAF1 NGFR NOTCH1 NOTO NPAS4 NUMBL PHF1 PITX1 PJA1 PJA2 PLK1 PNMA5 POM121 PRKAB2 PROP1 PRR20A PRR20B PRR20C PRR20D PRR20E PRR35 PSMF1 RAMAC RBFOX1 RBFOX2 RBM23 RBPMS RBPMS2 RFX1 RHOXF2 RNF6 RNF8 ROR2 RUSC1 RXFP4 SIM2 SIRT7 SMAP2 SMN1 SMN2 SNRPC SOX10 SOX5 TBX6 TFG TIAL1 TLX3 TRAF4 TRIM28 TSGA10IP TTC23 TTC32 TUBA4A UBQLN2 UNC5A VENTX XIAP YTHDF1 ZFYVE26 ZIC1 ZNF488 ZNF688
Entrez ID		8669	9500
HPRD ID		04883	02202
Ensembl ID		ENSG00000104131	ENSG00000179222
Uniprot IDs		A0A024R5S5 O75822	Q9Y5V3
PDB IDs		2KRB 3BPJ 6YBW 6ZMW 6ZVJ
Enriched GO Terms of Interacting Partners?
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