ABCE1 and RNASEL

Data Source:
HPRD (in vitro)

		ABCE1	RNASEL
Description		ATP binding cassette subfamily E member 1	ribonuclease L
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GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol Eukaryotic Translation Initiation Factor 3 Complex Membrane	Cellular_component Mitochondrial Matrix Cytosol Nuclear Matrix
	Molecular Function	Iron Ion Binding Protein Binding ATP Binding ATPase Activity Ribosomal Small Subunit Binding Endoribonuclease Inhibitor Activity	RNA Binding Endoribonuclease Activity Ribonuclease Activity Protein Kinase Activity Protein Binding ATP Binding RRNA Binding Ribonucleoprotein Complex Binding Metal Ion Binding
	Biological Process	Ribosomal Subunit Export From Nucleus Translational Initiation Translational Termination Viral Process Defense Response To Virus Regulation Of Type I Interferon-mediated Signaling Pathway Negative Regulation Of Endoribonuclease Activity	RRNA Processing RNA Processing MRNA Processing Protein Phosphorylation Regulation Of MRNA Stability Negative Regulation Of Viral Genome Replication Fat Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Glucose Import Defense Response To Virus Type I Interferon Signaling Pathway Regulation Of Type I Interferon-mediated Signaling Pathway RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways		OAS antiviral response Interferon alpha/beta signaling	OAS antiviral response Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Malaria ( 31844061) Subcortical volume (MOSTest) ( 32665545) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Morning vs. evening chronotype ( 26835600) Multiple sclerosis ( 23412934)
Interacting Genes		3 interacting genes: EIF3J RNASE2 RNASEL	3 interacting genes: ABCE1 AR TCF12
Entrez ID		6059	6041
HPRD ID		03132	01590
Ensembl ID		ENSG00000164163	ENSG00000135828
Uniprot IDs		P61221	Q05823
PDB IDs		6ZME 6ZVJ 7A09	1WDY 4G8K 4G8L 4OAU 4OAV
Enriched GO Terms of Interacting Partners?
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