Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
RNF2 and UBE2U
Data Source:
BioGRID
(two hybrid)
RNF2
UBE2U
Description
ring finger protein 2
ubiquitin conjugating enzyme E2 U
Image
GO Annotations
Cellular Component
Ubiquitin Ligase Complex
Euchromatin
Sex Chromatin
Nucleus
Nucleoplasm
Nuclear Body
PcG Protein Complex
PRC1 Complex
MLL1 Complex
HULC Complex
Molecular Function
Chromatin Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Ubiquitin Protein Ligase Activity
RING-like Zinc Finger Domain Binding
Protein Binding
ATP Binding
Ubiquitin Conjugating Enzyme Activity
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Mitotic Cell Cycle
Gastrulation With Mouth Forming Second
Germ Cell Development
Anterior/posterior Axis Specification
Gene Expression
Histone H2A Monoubiquitination
Histone H2A-K119 Monoubiquitination
Negative Regulation Of DNA-binding Transcription Factor Activity
Negative Regulation Of G0 To G1 Transition
Protein Polyubiquitination
DNA Repair
Histone Ubiquitination
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways
Oxidative Stress Induced Senescence
SUMOylation of DNA damage response and repair proteins
SUMOylation of transcription cofactors
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA methylation proteins
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Transcriptional Regulation by E2F6
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Clopidogrel active metabolite levels (
28207573
)
Itch intensity from mosquito bite adjusted by bite size (
28199695
)
Obesity-related traits (
23251661
)
Severe bacterial meningitis (
31092817
)
Interacting Genes
59 interacting genes:
ABCB1
AMBRA1
AUTS2
BAALC
BMI1
CASP3
CASP9
CBX2
CBX4
DYSF
ERG
H2AC18
H2AC20
H2AC4
H3-4
KAT8
KMT2A
MBD1
MTNR1A
OTUD6A
PCGF1
PCGF2
PCGF3
PCGF6
PGP
PHB2
PHC1
PHC2
PLK1
PSMC4
RING1
RRM1
RYBP
SIK1
SMURF2
SSX2
TARDBP
TFCP2
TSC22D2
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E2
UBE2E3
UBE2H
UBE2J1
UBE2K
UBE2L3
UBE2U
UBE2V1
UBE2V2
UBE2W
USP11
USP19
WASHC1
YAF2
68 interacting genes:
ANAPC11
BARD1
BFAR
CADPS2
CBL
CGRRF1
DTX1
DZIP3
GOLGA2
KAT6A
MDM2
MIB1
MIB2
MID2
MKRN3
MUL1
PCGF1
PCGF2
PCGF6
PJA1
PML
RBCK1
RNF10
RNF11
RNF113A
RNF113B
RNF114
RNF125
RNF139
RNF14
RNF144B
RNF150
RNF166
RNF17
RNF170
RNF181
RNF2
RNF25
RNF26
RNF41
RNF5
RNFT1
SYVN1
TRAIP
TRIM15
TRIM2
TRIM23
TRIM24
TRIM27
TRIM28
TRIM3
TRIM32
TRIM34
TRIM35
TRIM37
TRIM38
TRIM46
TRIM47
TRIM5
TRIM54
TRIM63
TRIM65
TRIM68
TRIM74
UBA1
VPS11
VPS41
ZSWIM2
Entrez ID
6045
148581
HPRD ID
07028
14599
Ensembl ID
ENSG00000121481
ENSG00000177414
Uniprot IDs
Q99496
A0A140VJY9
Q5VVX9
PDB IDs
2H0D
3GS2
3H8H
3IXS
3RPG
4R8P
4S3O
1YRV
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?