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UBE2U and PCGF1
Data Source:
BioGRID
(two hybrid)
UBE2U
PCGF1
Description
ubiquitin conjugating enzyme E2 U
polycomb group ring finger 1
Image
GO Annotations
Cellular Component
HULC Complex
Nucleus
Nucleoplasm
PcG Protein Complex
PRC1 Complex
Molecular Function
Protein Binding
ATP Binding
Ubiquitin Conjugating Enzyme Activity
Protein Binding
Protein C-terminus Binding
Metal Ion Binding
Promoter-specific Chromatin Binding
Biological Process
Protein Polyubiquitination
DNA Repair
Histone Ubiquitination
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Transcription By RNA Polymerase II
Chromatin Silencing
Regulation Of Transcription, DNA-templated
Histone H2A Monoubiquitination
Histone H2A-K119 Monoubiquitination
Pathways
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Severe bacterial meningitis (
31092817
)
Interacting Genes
68 interacting genes:
ANAPC11
BARD1
BFAR
CADPS2
CBL
CGRRF1
DTX1
DZIP3
GOLGA2
KAT6A
MDM2
MIB1
MIB2
MID2
MKRN3
MUL1
PCGF1
PCGF2
PCGF6
PJA1
PML
RBCK1
RNF10
RNF11
RNF113A
RNF113B
RNF114
RNF125
RNF139
RNF14
RNF144B
RNF150
RNF166
RNF17
RNF170
RNF181
RNF2
RNF25
RNF26
RNF41
RNF5
RNFT1
SYVN1
TRAIP
TRIM15
TRIM2
TRIM23
TRIM24
TRIM27
TRIM28
TRIM3
TRIM32
TRIM34
TRIM35
TRIM37
TRIM38
TRIM46
TRIM47
TRIM5
TRIM54
TRIM63
TRIM65
TRIM68
TRIM74
UBA1
VPS11
VPS41
ZSWIM2
12 interacting genes:
BCOR
CALCOCO2
CBX6
CBX7
FCHO1
MUC7
PCGF5
RNF125
RNF2
TRIM55
UBE2D3
UBE2U
Entrez ID
148581
84759
HPRD ID
14599
11404
Ensembl ID
ENSG00000177414
ENSG00000115289
Uniprot IDs
A0A140VJY9
Q5VVX9
Q9BSM1
PDB IDs
1YRV
4HPL
4HPM
5JH5
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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