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RNF2 and UBE2J1
Data Source:
BioGRID
(two hybrid)
RNF2
UBE2J1
Description
ring finger protein 2
ubiquitin conjugating enzyme E2 J1
Image
No pdb structure
GO Annotations
Cellular Component
Ubiquitin Ligase Complex
Euchromatin
Sex Chromatin
Nucleus
Nucleoplasm
Nuclear Body
PcG Protein Complex
PRC1 Complex
MLL1 Complex
Nucleus
Endoplasmic Reticulum Membrane
Integral Component Of Membrane
Molecular Function
Chromatin Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Ubiquitin Protein Ligase Activity
RING-like Zinc Finger Domain Binding
Protein Binding
ATP Binding
Ubiquitin Protein Ligase Binding
Ubiquitin Conjugating Enzyme Activity
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Mitotic Cell Cycle
Gastrulation With Mouth Forming Second
Germ Cell Development
Anterior/posterior Axis Specification
Gene Expression
Histone H2A Monoubiquitination
Histone H2A-K119 Monoubiquitination
Negative Regulation Of DNA-binding Transcription Factor Activity
Negative Regulation Of G0 To G1 Transition
Protein Polyubiquitination
Spermatid Development
Protein N-linked Glycosylation Via Asparagine
Ubiquitin-dependent ERAD Pathway
Regulation Of Tumor Necrosis Factor Production
Negative Regulation Of Retrograde Protein Transport, ER To Cytosol
Pathways
Oxidative Stress Induced Senescence
SUMOylation of DNA damage response and repair proteins
SUMOylation of transcription cofactors
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA methylation proteins
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Transcriptional Regulation by E2F6
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Clopidogrel active metabolite levels (
28207573
)
Itch intensity from mosquito bite adjusted by bite size (
28199695
)
Obesity-related traits (
23251661
)
Interacting Genes
59 interacting genes:
ABCB1
AMBRA1
AUTS2
BAALC
BMI1
CASP3
CASP9
CBX2
CBX4
DYSF
ERG
H2AC18
H2AC20
H2AC4
H3-4
KAT8
KMT2A
MBD1
MTNR1A
OTUD6A
PCGF1
PCGF2
PCGF3
PCGF6
PGP
PHB2
PHC1
PHC2
PLK1
PSMC4
RING1
RRM1
RYBP
SIK1
SMURF2
SSX2
TARDBP
TFCP2
TSC22D2
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E2
UBE2E3
UBE2H
UBE2J1
UBE2K
UBE2L3
UBE2U
UBE2V1
UBE2V2
UBE2W
USP11
USP19
WASHC1
YAF2
48 interacting genes:
AQP2
BIRC2
BRCA1
CD79A
CDS1
CLTRN
CREB3
CYB561
DERL1
DIO2
EBP
ELOVL4
FAM209A
FAM210B
FCER1G
GKN1
GOLT1A
JAGN1
LAPTM5
LRSAM1
LY6G6C
LYVE1
MAPKAPK2
MFSD14B
MFSD3
MS4A6E
PJA2
PLPPR2
PRKN
PROKR2
REEP4
RNF2
SEC11C
SLC10A6
SLC26A5
TLCD4
TM4SF18
TM4SF19
TMEM14B
TMEM31
TMEM51
TMX2
TOPORS
TRHR
TRIM27
TRIM63
UBA1
UBC
Entrez ID
6045
51465
HPRD ID
07028
15599
Ensembl ID
ENSG00000121481
ENSG00000198833
Uniprot IDs
Q99496
Q9Y385
PDB IDs
2H0D
3GS2
3H8H
3IXS
3RPG
4R8P
4S3O
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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