RFC5 and LRIF1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RFC5	LRIF1
Description		replication factor C subunit 5	ligand dependent nuclear receptor interacting factor 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm DNA Replication Factor C Complex Ctf18 RFC-like Complex	Chromosome, Telomeric Region Barr Body Nucleoplasm Nuclear Matrix Centriolar Satellite
	Molecular Function	DNA Clamp Loader Activity Protein Binding ATP Binding Single-stranded DNA Helicase Activity Enzyme Binding	Protein Binding Retinoic Acid Receptor Binding
	Biological Process	DNA Replication DNA-dependent DNA Replication DNA Repair Transcription-coupled Nucleotide-excision Repair Nucleotide-excision Repair, DNA Incision, 5'-to Lesion Nucleotide-excision Repair, DNA Gap Filling Translesion Synthesis Telomere Maintenance Via Semi-conservative Replication DNA Duplex Unwinding Nucleotide-excision Repair, DNA Incision Error-prone Translesion Synthesis DNA Damage Response, Detection Of DNA Damage Error-free Translesion Synthesis Positive Regulation Of DNA-directed DNA Polymerase Activity Regulation Of Signal Transduction By P53 Class Mediator	Regulation Of Transcription, DNA-templated Dosage Compensation By Inactivation Of X Chromosome
Pathways		Translesion synthesis by REV1 Recognition of DNA damage by PCNA-containing replication complex Translesion Synthesis by POLH Polymerase switching on the C-strand of the telomere Activation of ATR in response to replication stress PCNA-Dependent Long Patch Base Excision Repair Translesion synthesis by POLK Translesion synthesis by POLI Termination of translesion DNA synthesis HDR through Single Strand Annealing (SSA) HDR through Homologous Recombination (HRR) Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Gap-filling DNA repair synthesis and ligation in GG-NER Dual Incision in GG-NER Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER Regulation of TP53 Activity through Phosphorylation Polymerase switching G2/M DNA damage checkpoint
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Neurociticism ( 29500382) Obesity-related traits ( 23251661) Physiological traits ( 31902109)	Bone mineral content ( 31790847) Intraocular pressure ( 30591961)
Interacting Genes		35 interacting genes: ARID5A BIRC2 CCNC CHTF18 COPS6 DAPK1 DDIT4L EEF1A1 EML2 EXOSC8 FAM166B KRT34 LMO3 LRIF1 MED31 N4BP3 NAB2 NR5A1 PCNA PPP1R16B PTEN RBM48 RFC2 RFC4 SUMO2 TASOR2 TRIM38 TSNAX UNC119 XAF1 XIAP YPEL3 ZMAT1 ZNF19 ZNF426	144 interacting genes: AKR1C3 ANKRD24 ANXA1 ANXA7 APLP1 ARL3 ATF3 ATP1B1 BANP BARD1 BMI1 BOC BRD7 BRMS1 CALR CBX1 CBX3 CBX5 CCDC106 CDC42 CDKN1A CDKN2C CETN3 CHD3 CKMT2 COX17 CPE CRACR2A CRADD CRCP CRCT1 DDIT4 EIF6 ESR1 ETHE1 FAS FEZ1 FHL2 FOSL2 FXR1 GADD45G GC GIT1 GPRASP2 GSTM4 H3-4 HAP1 HLA-DQA1 HMGB1 HMOX2 HSPB1 HSPB3 HSPBP1 HSPE1 ID2 IMMT KAT5 KAT7 KBTBD7 KCNE3 KLHL20 KLK10 LAMA4 LAMTOR5 MAD2L1BP MLLT3 MNAT1 MOB4 MPHOSPH6 MRPS12 MRPS6 NACA NOC2L NR3C1 NRBP1 NTAQ1 PAEP PAFAH1B3 PCDHA4 PDCD5 PFDN1 PFN1 PIAS4 PIN1 PLEKHA4 PNP POLR1C POLR2C POLR3F PPARG PQBP1 PRKAB2 PRKAR2A PRMT1 PSG9 PSMD11 PSMD2 PSPC1 RAB27A RAP1B RARA RBM5 RCC1 RFC5 RHOH RIT1 RNF10 RORA RPA2 RPL37A RPLP1 RRM1 S100A8 SAT1 SELENBP1 SERPINB9 SETDB1 SMN1 SNRPN SNU13 SPATA18 SPG7 STX5 SULT1E1 SUPT4H1 SUV39H2 TAF1D TDGF1 TGIF1 THRB TK1 TRBV2 TRDMT1 TSC22D1 TSEN15 TSPAN6 UBE2V2 UNC119 VIM VPS26C WDR62 WWC1 ZNF24 ZNF410
Entrez ID		5985	55791
HPRD ID		02677	17975
Ensembl ID		ENSG00000111445	ENSG00000121931
Uniprot IDs		P40937 Q59GW7	Q5T3J3
PDB IDs		1LFS 6VVO
Enriched GO Terms of Interacting Partners?
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