RAB2A and GDI2

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		RAB2A	GDI2
Description		RAB2A, member RAS oncogene family	GDP dissociation inhibitor 2
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleus Lysosomal Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Melanosome Extracellular Exosome	Extracellular Region Cytoplasm Cytosol Focal Adhesion Membrane Vesicle Secretory Granule Lumen Azurophil Granule Lumen Synapse Extracellular Exosome
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding	RNA Binding Rab GDP-dissociation Inhibitor Activity GTPase Activator Activity Protein Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Organization Protein Transport Post-translational Protein Modification	Signal Transduction Small GTPase Mediated Signal Transduction Protein Transport Vesicle-mediated Transport Neutrophil Degranulation Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Golgi Cisternae Pericentriolar Stack Reorganization RAB geranylgeranylation	Neutrophil degranulation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Autoimmune thyroid disease ( 32581359) Estimated glomerular filtration rate ( 31152163) Low density lipoprotein cholesterol levels ( 32154731) Neutrophil count ( 32888494) Systemic sclerosis ( 31672989) Total cholesterol levels ( 29083408)	Blood protein levels ( 30072576) Cutaneous malignant melanoma ( 32341527) Osteosarcoma ( 23727862)
Interacting Genes		27 interacting genes: BLZF1 CBFB CCDC125 CFL2 FAM114A1 FAM114A2 FAM71A FAM71C FAM71F2 FRMD1 GAPDH GDI2 GOLGA2 GORASP2 HES6 ICA1 MAPK6 MAPKAPK3 PMAIP1 PRKCI RBSN RGS2 SGSM2 STAMBPL1 TBC1D25 TMEM70 TRIM7	9 interacting genes: GLRA2 HSPB1 LINC01554 RAB11A RAB2A RAB4A RAB5A RAB8A RAB9A
Entrez ID		5862	2665
HPRD ID		01539	02863
Ensembl ID		ENSG00000104388	ENSG00000057608
Uniprot IDs		A0A024R7V6 P61019	P50395 Q6IAT1
PDB IDs		1Z0A
Enriched GO Terms of Interacting Partners?
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