RAB2A and CFL2

Data Source:
BioGRID (two hybrid)

		RAB2A	CFL2
Description		RAB2A, member RAS oncogene family	cofilin 2
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleus Lysosomal Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Melanosome Extracellular Exosome	Extracellular Space Cytoplasm Actin Cytoskeleton Nuclear Matrix Z Disc I Band Extracellular Exosome
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding	Protein Binding Actin Filament Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Organization Protein Transport Post-translational Protein Modification	Skeletal Muscle Tissue Development Actin Filament Depolymerization Actin Filament Fragmentation Positive Regulation Of Actin Filament Depolymerization Sarcomere Organization Muscle Cell Cellular Homeostasis Cell Motility Actin Filament Severing
Pathways		Golgi Cisternae Pericentriolar Stack Reorganization RAB geranylgeranylation
Drugs
Diseases			Nemaline myopathy
GWAS		Autoimmune thyroid disease ( 32581359) Estimated glomerular filtration rate ( 31152163) Low density lipoprotein cholesterol levels ( 32154731) Neutrophil count ( 32888494) Systemic sclerosis ( 31672989) Total cholesterol levels ( 29083408)	Atrial fibrillation ( 30061737 29892015) Hip circumference adjusted for BMI ( 28552196)
Interacting Genes		27 interacting genes: BLZF1 CBFB CCDC125 CFL2 FAM114A1 FAM114A2 FAM71A FAM71C FAM71F2 FRMD1 GAPDH GDI2 GOLGA2 GORASP2 HES6 ICA1 MAPK6 MAPKAPK3 PMAIP1 PRKCI RBSN RGS2 SGSM2 STAMBPL1 TBC1D25 TMEM70 TRIM7	13 interacting genes: ACTB ACTG1 CAP2 CFL1 DSTN LIMK1 POT1 RAB2A RNF4 SSH1 STK11 TRIM7 UBE2I
Entrez ID		5862	1073
HPRD ID		01539	03262
Ensembl ID		ENSG00000104388	ENSG00000165410
Uniprot IDs		A0A024R7V6 P61019	Q549N0 Q9Y281
PDB IDs		1Z0A
Enriched GO Terms of Interacting Partners?
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