GDI2 and RAB9A

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro)

		GDI2	RAB9A
Description		GDP dissociation inhibitor 2	RAB9A, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol Focal Adhesion Membrane Vesicle Secretory Granule Lumen Azurophil Granule Lumen Synapse Extracellular Exosome	Lysosome Late Endosome Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Transport Vesicle Phagocytic Vesicle Membrane Trans-Golgi Network Membrane Melanosome Phagocytic Vesicle Extracellular Exosome
	Molecular Function	RNA Binding Rab GDP-dissociation Inhibitor Activity GTPase Activator Activity Protein Binding	GTPase Activity Protein Binding GTP Binding GDP Binding
	Biological Process	Signal Transduction Small GTPase Mediated Signal Transduction Protein Transport Vesicle-mediated Transport Neutrophil Degranulation Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction	Protein Transport Rab Protein Signal Transduction Regulation Of Protein Localization Retrograde Transport, Endosome To Golgi Positive Regulation Of Exocytosis Negative Regulation By Host Of Symbiont Molecular Function
Pathways		Neutrophil degranulation RAB GEFs exchange GTP for GDP on RABs	Retrograde transport at the Trans-Golgi-Network RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs RHOBTB3 ATPase cycle
Drugs			Guanosine-5'-Diphosphate
Diseases
GWAS		Blood protein levels ( 30072576) Cutaneous malignant melanoma ( 32341527) Osteosarcoma ( 23727862)	Red cell distribution width ( 32888494)
Interacting Genes		9 interacting genes: GLRA2 HSPB1 LINC01554 RAB11A RAB2A RAB4A RAB5A RAB8A RAB9A	8 interacting genes: BCL3 GDI1 GDI2 PLIN3 RABEPK RHOBTB3 TM9SF2 TRIM14
Entrez ID		2665	9367
HPRD ID		02863	02236
Ensembl ID		ENSG00000057608	ENSG00000123595
Uniprot IDs		P50395 Q6IAT1	A0A024RBV5 P51151
PDB IDs			1WMS
Enriched GO Terms of Interacting Partners?
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