BBS2 and WRNIP1

Data Source:
BioGRID (affinity chromatography technology)

		BBS2	WRNIP1
Description		Bardet-Biedl syndrome 2	WRN helicase interacting protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Microvillus Membrane Motile Cilium Stereocilium BBSome Ciliary Basal Body Neuron Projection Ciliary Membrane	Chromosome, Telomeric Region Nucleus Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Polymerase II Repressing Transcription Factor Binding Protein Binding	DNA Binding Protein Binding ATP Binding Enzyme Activator Activity ATPase Activity Single-stranded DNA Helicase Activity Identical Protein Binding Metal Ion Binding
	Biological Process	Sperm Axoneme Assembly Visual Perception Protein Localization Negative Regulation Of Gene Expression Artery Smooth Muscle Contraction Striatum Development Hippocampus Development Cerebral Cortex Development Adult Behavior Melanosome Transport Protein Localization To Organelle Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway Negative Regulation Of Multicellular Organism Growth Positive Regulation Of Multicellular Organism Growth Vasodilation Golgi To Plasma Membrane Protein Transport Fat Cell Differentiation Photoreceptor Cell Maintenance Brain Morphogenesis Cartilage Development Cilium Assembly Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Non-motile Cilium Assembly	DNA Synthesis Involved In DNA Repair DNA-dependent DNA Replication Regulation Of DNA Repair Regulation Of DNA-dependent DNA Replication Initiation DNA Duplex Unwinding Innate Immune Response Regulation Of Catalytic Activity
Pathways		BBSome-mediated cargo-targeting to cilium
Drugs
Diseases		Bardet-Biedl syndrome (BBS)
GWAS			Plateletcrit ( 32888494)
Interacting Genes		15 interacting genes: BHMT EEF1A1 EPAS1 EXOC7 FHOD1 FNDC3B HNRNPF HSCB KRT18 LMO4 MDFI NRF1 PAX2 PSME3 RBPMS	12 interacting genes: ABL1 ERBB3 PCNA PIK3R3 PIN1 POLD1 POLD2 POLD4 TOLLIP TRIM14 UBC WRN
Entrez ID		583	56897
HPRD ID		05855	10494
Ensembl ID		ENSG00000125124	ENSG00000124535
Uniprot IDs		Q9BXC9	Q96S55
PDB IDs			3VHS 3VHT
Enriched GO Terms of Interacting Partners?
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