BBS2 and HSCB

Data Source:
BioGRID (two hybrid)

		BBS2	HSCB
Description		Bardet-Biedl syndrome 2	HscB mitochondrial iron-sulfur cluster cochaperone
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Microvillus Membrane Motile Cilium Stereocilium BBSome Ciliary Basal Body Neuron Projection Ciliary Membrane	Nucleoplasm Cytoplasm Mitochondrion Cytosol
	Molecular Function	RNA Polymerase II Repressing Transcription Factor Binding Protein Binding	ATPase Activator Activity Molecular_function Protein Binding Identical Protein Binding Metal Ion Binding Chaperone Binding
	Biological Process	Sperm Axoneme Assembly Visual Perception Protein Localization Negative Regulation Of Gene Expression Artery Smooth Muscle Contraction Striatum Development Hippocampus Development Cerebral Cortex Development Adult Behavior Melanosome Transport Protein Localization To Organelle Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway Negative Regulation Of Multicellular Organism Growth Positive Regulation Of Multicellular Organism Growth Vasodilation Golgi To Plasma Membrane Protein Transport Fat Cell Differentiation Photoreceptor Cell Maintenance Brain Morphogenesis Cartilage Development Cilium Assembly Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Non-motile Cilium Assembly	Iron-sulfur Cluster Assembly Positive Regulation Of ATPase Activity [2Fe-2S] Cluster Assembly Protein Complex Oligomerization Protein Maturation By Iron-sulfur Cluster Transfer
Pathways		BBSome-mediated cargo-targeting to cilium	Mitochondrial protein import Mitochondrial protein import Mitochondrial iron-sulfur cluster biogenesis
Drugs
Diseases		Bardet-Biedl syndrome (BBS)
GWAS			Breast size ( 27182965) Diastolic blood pressure ( 27841878) Esophageal cancer and gastric cancer ( 20729852) Mean platelet volume ( 32888494) Myeloproliferative neoplasms ( 33057200) Pancreatic cancer ( 25086665) Red cell distribution width ( 27863252) Systolic blood pressure ( 27841878)
Interacting Genes		15 interacting genes: BHMT EEF1A1 EPAS1 EXOC7 FHOD1 FNDC3B HNRNPF HSCB KRT18 LMO4 MDFI NRF1 PAX2 PSME3 RBPMS	4 interacting genes: AGTRAP BBS1 BBS2 BBS4
Entrez ID		583	150274
HPRD ID		05855	16289
Ensembl ID		ENSG00000125124	ENSG00000100209
Uniprot IDs		Q9BXC9	A0A384NYJ4 B0QYH2 Q8IWL3
PDB IDs			3BVO
Enriched GO Terms of Interacting Partners?
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