BBS2 and EXOC7

Data Source:
BioGRID (two hybrid)

		BBS2	EXOC7
Description		Bardet-Biedl syndrome 2	exocyst complex component 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Microvillus Membrane Motile Cilium Stereocilium BBSome Ciliary Basal Body Neuron Projection Ciliary Membrane	Exocyst Microtubule Organizing Center Cytosol Plasma Membrane Membrane Growth Cone Membrane Centriolar Satellite Flemming Body
	Molecular Function	RNA Polymerase II Repressing Transcription Factor Binding Protein Binding	Protein Binding
	Biological Process	Sperm Axoneme Assembly Visual Perception Protein Localization Negative Regulation Of Gene Expression Artery Smooth Muscle Contraction Striatum Development Hippocampus Development Cerebral Cortex Development Adult Behavior Melanosome Transport Protein Localization To Organelle Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway Negative Regulation Of Multicellular Organism Growth Positive Regulation Of Multicellular Organism Growth Vasodilation Golgi To Plasma Membrane Protein Transport Fat Cell Differentiation Photoreceptor Cell Maintenance Brain Morphogenesis Cartilage Development Cilium Assembly Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Non-motile Cilium Assembly	Exocytosis Protein Transport Regulation Of Macroautophagy Regulation Of Entry Of Bacterium Into Host Cell
Pathways		BBSome-mediated cargo-targeting to cilium	Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs
Diseases		Bardet-Biedl syndrome (BBS)
GWAS			Body size at age 10 ( 32376654)
Interacting Genes		15 interacting genes: BHMT EEF1A1 EPAS1 EXOC7 FHOD1 FNDC3B HNRNPF HSCB KRT18 LMO4 MDFI NRF1 PAX2 PSME3 RBPMS	37 interacting genes: AKTIP ARFGEF2 ARPC1A BBS1 BBS2 BBS4 CCDC85B CCHCR1 CDC5L CT55 DISC1 DLG3 EXOC2 EXOC4 FBXO28 GRIN2B HGS IFT20 KDM1A KIFC3 KXD1 MSGN1 PLEKHF2 PRPF19 RALA RALY RHOQ RTN4IP1 SAPCD2 SMARCE1 SNAPIN SSC5D TRAF4 TRIM54 USHBP1 YAE1 ZC3H14
Entrez ID		583	23265
HPRD ID		05855	16292
Ensembl ID		ENSG00000125124	ENSG00000182473
Uniprot IDs		Q9BXC9	B4DJ07 B5MCY9 Q63HP7 Q9UPT5
PDB IDs
Enriched GO Terms of Interacting Partners?
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