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HOMEZ and CENPS
Data Source:
BioGRID
(two hybrid)
HOMEZ
CENPS
Description
homeobox and leucine zipper encoding
centromere protein S
Image
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Nucleolus
Cytosol
Condensed Chromosome Kinetochore
Nucleoplasm
Cytosol
Fanconi Anaemia Nuclear Complex
FANCM-MHF Complex
Molecular Function
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA Binding
DNA Binding
Chromatin Binding
Double-stranded DNA Binding
Protein Binding
Protein Heterodimerization Activity
Biological Process
Regulation Of Transcription By RNA Polymerase II
Resolution Of Meiotic Recombination Intermediates
DNA Repair
Cellular Response To DNA Damage Stimulus
Replication Fork Processing
Positive Regulation Of Protein Ubiquitination
CENP-A Containing Nucleosome Assembly
Interstrand Cross-link Repair
Cell Division
Kinetochore Assembly
Pathways
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Deposition of new CENPA-containing nucleosomes at the centromere
Fanconi Anemia Pathway
Mitotic Prometaphase
EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS
Height (
31562340
)
High light scatter reticulocyte count (
32888494
)
High light scatter reticulocyte percentage of red cells (
32888494
)
Mean platelet volume (
32888494
)
Pulse pressure (
27841878
)
Reticulocyte count (
32888494
)
Systolic blood pressure (
27841878
)
Interacting Genes
114 interacting genes:
ACTR10
AEN
ANKRD11
ANKRD2
ARHGAP9
ASB6
AXIN1
BIVM
BYSL
C2orf42
CBX8
CCDC13
CCDC187
CCHCR1
CCNK
CDC7
CENPS
CENPS-CORT
CFAP206
CTNNA3
DEF6
DGCR6
DHX16
DNTTIP1
EBF1
EIF4E2
ELOA
ENKD1
FAM90A1
FARS2
GAS8
GFAP
GPANK1
GRB2
HOXC8
HSF2BP
IL16
INO80B
JAKMIP2
KIFC3
KPNA2
LENG1
LGALS4
LMO1
LMO3
LNX1
LRRC7
LSM4
MAD2L1BP
MAFG
MAPK1
MED18
MORF4L2
MOS
MRPL11
NCK1
NCK2
NEIL2
NEK6
NXF1
OSGIN1
PARVG
PHF1
PHF19
PIBF1
PIN1
PLEKHA7
POLDIP3
PRKAA1
PRKAA2
PRPF18
PSMA1
RASL10A
RBM39
RNF8
RPGR
RPL9
RPP25
RPS25
SCNM1
SDCBP
SEC23A
SH3RF2
SMARCB1
SMARCD1
SMYD1
SNRPB2
SUMO2
SUMO3
TARS2
TBC1D30
TCEA2
TCEANC
TEAD4
TLE5
TRAF4
TSGA10IP
TXK
USF1
VEZF1
VPS9D1
ZBTB25
ZBTB7A
ZMYND19
ZNF165
ZNF250
ZNF280C
ZNF35
ZNF417
ZNF580
ZNF629
ZNF688
ZNF76
ZSCAN5B
4 interacting genes:
APP
CENPM
CENPX
HOMEZ
Entrez ID
57594
378708
HPRD ID
12167
18797
Ensembl ID
ENSG00000215271
ENSG00000175279
Uniprot IDs
Q8IX15
Q8N2Z9
PDB IDs
2ECC
2YS9
4DRA
4DRB
4E44
4E45
4NDY
4NE1
4NE3
4NE5
4NE6
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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