CENPS and CENPM

Data Source:
BioGRID (fluorescent resonance energy transfer)

		CENPS	CENPM
Description		centromere protein S	centromere protein M
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GO Annotations	Cellular Component	Condensed Chromosome Kinetochore Nucleoplasm Cytosol Fanconi Anaemia Nuclear Complex FANCM-MHF Complex	Condensed Chromosome Kinetochore Nucleoplasm Cytosol
	Molecular Function	DNA Binding Chromatin Binding Double-stranded DNA Binding Protein Binding Protein Heterodimerization Activity
	Biological Process	Resolution Of Meiotic Recombination Intermediates DNA Repair Cellular Response To DNA Damage Stimulus Replication Fork Processing Positive Regulation Of Protein Ubiquitination CENP-A Containing Nucleosome Assembly Interstrand Cross-link Repair Cell Division Kinetochore Assembly	CENP-A Containing Nucleosome Assembly
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Fanconi Anemia Pathway Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS			Birth weight ( 23202124) Processed meat consumption ( 32066663) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Interacting Genes		4 interacting genes: APP CENPM CENPX HOMEZ	2 interacting genes: CENPS H3C1
Entrez ID		378708	79019
HPRD ID		18797	12798
Ensembl ID		ENSG00000175279	ENSG00000100162
Uniprot IDs		Q8N2Z9	A0A024R1Q3 B1AHQ6 B1AHQ7 B1AHQ8 Q9NSP4
PDB IDs		4DRA 4DRB 4E44 4E45 4NDY 4NE1 4NE3 4NE5 4NE6	4P0T 4WAU
Enriched GO Terms of Interacting Partners?
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