CENPS and CENPX

Data Source:
BioGRID (pull down)

		CENPS	CENPX
Description		centromere protein S	centromere protein X
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GO Annotations	Cellular Component	Condensed Chromosome Kinetochore Nucleoplasm Cytosol Fanconi Anaemia Nuclear Complex FANCM-MHF Complex	Condensed Chromosome Kinetochore Nucleoplasm Fanconi Anaemia Nuclear Complex FANCM-MHF Complex
	Molecular Function	DNA Binding Chromatin Binding Double-stranded DNA Binding Protein Binding Protein Heterodimerization Activity	DNA Binding Double-stranded DNA Binding Protein Binding
	Biological Process	Resolution Of Meiotic Recombination Intermediates DNA Repair Cellular Response To DNA Damage Stimulus Replication Fork Processing Positive Regulation Of Protein Ubiquitination CENP-A Containing Nucleosome Assembly Interstrand Cross-link Repair Cell Division Kinetochore Assembly	Resolution Of Meiotic Recombination Intermediates Replication Fork Processing Positive Regulation Of Protein Ubiquitination CENP-A Containing Nucleosome Assembly Interstrand Cross-link Repair Cell Division Kinetochore Assembly
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Fanconi Anemia Pathway Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	Deposition of new CENPA-containing nucleosomes at the centromere Fanconi Anemia Pathway
Drugs
Diseases
GWAS
Interacting Genes		4 interacting genes: APP CENPM CENPX HOMEZ	7 interacting genes: CENPS FANCM NKX3-1 REL TP53 TRIM54 UBE2I
Entrez ID		378708	201254
HPRD ID		18797	18121
Ensembl ID		ENSG00000175279	ENSG00000169689
Uniprot IDs		Q8N2Z9	A8MT69 J3QRS1
PDB IDs		4DRA 4DRB 4E44 4E45 4NDY 4NE1 4NE3 4NE5 4NE6	4DRA 4DRB 4E44 4E45 4NDY 4NE1 4NE3 4NE5 4NE6
Enriched GO Terms of Interacting Partners?
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