HOMEZ and ARHGAP9

Data Source:
BioGRID (two hybrid)

		HOMEZ	ARHGAP9
Description		homeobox and leucine zipper encoding	Rho GTPase activating protein 9
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Nucleolus Cytosol	Extracellular Region Cytoplasm Cytosol Secretory Granule Lumen
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding	GTPase Activator Activity Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Signal Transduction Regulation Of GTPase Activity Neutrophil Degranulation Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways			Rho GTPase cycle Neutrophil degranulation
Drugs
Diseases
GWAS		Height ( 31562340) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean platelet volume ( 32888494) Pulse pressure ( 27841878) Reticulocyte count ( 32888494) Systolic blood pressure ( 27841878)	Monocyte percentage of white cells ( 32888494)
Interacting Genes		114 interacting genes: ACTR10 AEN ANKRD11 ANKRD2 ARHGAP9 ASB6 AXIN1 BIVM BYSL C2orf42 CBX8 CCDC13 CCDC187 CCHCR1 CCNK CDC7 CENPS CENPS-CORT CFAP206 CTNNA3 DEF6 DGCR6 DHX16 DNTTIP1 EBF1 EIF4E2 ELOA ENKD1 FAM90A1 FARS2 GAS8 GFAP GPANK1 GRB2 HOXC8 HSF2BP IL16 INO80B JAKMIP2 KIFC3 KPNA2 LENG1 LGALS4 LMO1 LMO3 LNX1 LRRC7 LSM4 MAD2L1BP MAFG MAPK1 MED18 MORF4L2 MOS MRPL11 NCK1 NCK2 NEIL2 NEK6 NXF1 OSGIN1 PARVG PHF1 PHF19 PIBF1 PIN1 PLEKHA7 POLDIP3 PRKAA1 PRKAA2 PRPF18 PSMA1 RASL10A RBM39 RNF8 RPGR RPL9 RPP25 RPS25 SCNM1 SDCBP SEC23A SH3RF2 SMARCB1 SMARCD1 SMYD1 SNRPB2 SUMO2 SUMO3 TARS2 TBC1D30 TCEA2 TCEANC TEAD4 TLE5 TRAF4 TSGA10IP TXK USF1 VEZF1 VPS9D1 ZBTB25 ZBTB7A ZMYND19 ZNF165 ZNF250 ZNF280C ZNF35 ZNF417 ZNF580 ZNF629 ZNF688 ZNF76 ZSCAN5B	16 interacting genes: ABI3 APP CYSRT1 FASLG FHL2 GOLGA6A GOLGA6L9 HOMEZ MRPL38 NME7 RAC1 RBPMS RUNX1T1 SMAD9 SNRPC TSC22D4
Entrez ID		57594	64333
HPRD ID		12167	06449
Ensembl ID		ENSG00000215271	ENSG00000123329
Uniprot IDs		Q8IX15	B3KQ74 J3KPQ4 Q9BRR9
PDB IDs		2ECC 2YS9	2P0D 2P0F 2P0H
Enriched GO Terms of Interacting Partners?
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