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HOMEZ and SUMO3
Data Source:
BioGRID
(two hybrid)
HOMEZ
SUMO3
Description
homeobox and leucine zipper encoding
small ubiquitin like modifier 3
Image
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Nucleolus
Cytosol
Kinetochore
Nucleus
Nucleoplasm
Cytoplasm
PML Body
Molecular Function
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA Binding
Protein Binding
Protein Tag
Ubiquitin-like Protein Ligase Binding
Biological Process
Regulation Of Transcription By RNA Polymerase II
Protein Sumoylation
Negative Regulation Of DNA Binding
Regulation Of Protein Localization To Nucleus
Pathways
SUMO is conjugated to E1 (UBA2:SAE1)
SUMO is transferred from E1 to E2 (UBE2I, UBC9)
SUMO is proteolytically processed
SUMOylation of DNA damage response and repair proteins
SUMOylation of transcription factors
SUMOylation of transcription cofactors
SUMOylation of intracellular receptors
SUMOylation of intracellular receptors
SUMOylation of chromatin organization proteins
SUMOylation of DNA replication proteins
SUMOylation of immune response proteins
Formation of Incision Complex in GG-NER
Drugs
Diseases
GWAS
Height (
31562340
)
High light scatter reticulocyte count (
32888494
)
High light scatter reticulocyte percentage of red cells (
32888494
)
Mean platelet volume (
32888494
)
Pulse pressure (
27841878
)
Reticulocyte count (
32888494
)
Systolic blood pressure (
27841878
)
Delirium (
29631748
)
Interacting Genes
114 interacting genes:
ACTR10
AEN
ANKRD11
ANKRD2
ARHGAP9
ASB6
AXIN1
BIVM
BYSL
C2orf42
CBX8
CCDC13
CCDC187
CCHCR1
CCNK
CDC7
CENPS
CENPS-CORT
CFAP206
CTNNA3
DEF6
DGCR6
DHX16
DNTTIP1
EBF1
EIF4E2
ELOA
ENKD1
FAM90A1
FARS2
GAS8
GFAP
GPANK1
GRB2
HOXC8
HSF2BP
IL16
INO80B
JAKMIP2
KIFC3
KPNA2
LENG1
LGALS4
LMO1
LMO3
LNX1
LRRC7
LSM4
MAD2L1BP
MAFG
MAPK1
MED18
MORF4L2
MOS
MRPL11
NCK1
NCK2
NEIL2
NEK6
NXF1
OSGIN1
PARVG
PHF1
PHF19
PIBF1
PIN1
PLEKHA7
POLDIP3
PRKAA1
PRKAA2
PRPF18
PSMA1
RASL10A
RBM39
RNF8
RPGR
RPL9
RPP25
RPS25
SCNM1
SDCBP
SEC23A
SH3RF2
SMARCB1
SMARCD1
SMYD1
SNRPB2
SUMO2
SUMO3
TARS2
TBC1D30
TCEA2
TCEANC
TEAD4
TLE5
TRAF4
TSGA10IP
TXK
USF1
VEZF1
VPS9D1
ZBTB25
ZBTB7A
ZMYND19
ZNF165
ZNF250
ZNF280C
ZNF35
ZNF417
ZNF580
ZNF629
ZNF688
ZNF76
ZSCAN5B
53 interacting genes:
ANXA7
BLM
CCNE2
CDKN1A
CEBPA
CHAF1A
CUL3
DAXX
EGLN3
FAM221A
FOS
HIPK2
HOMEZ
HSF1
HSF2
JUN
KALRN
MAPKAPK3
PFDN1
PIAS1
PIAS2
PIAS3
PIAS4
PML
RANGAP1
RNF111
RNF8
SAE1
SENP1
SENP2
SENP5
SMN1
SOX10
SOX6
SP100
TDG
TDP2
TK1
TP53BP2
TTR
UBA2
UBE2I
UBE3A
UPF2
USP25
USPL1
VIM
WWTR1
YAP1
ZBTB33
ZBTB39
ZCCHC12
ZNF496
Entrez ID
57594
6612
HPRD ID
12167
03754
Ensembl ID
ENSG00000215271
ENSG00000184900
Uniprot IDs
Q8IX15
P55854
PDB IDs
2ECC
2YS9
1U4A
2IO1
2MP2
6K5R
6NNQ
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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