BANP and TERF2IP

Data Source:
BioGRID (two hybrid)

		BANP	TERF2IP
Description		BTG3 associated nuclear protein	TERF2 interacting protein
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nuclear Body	Nuclear Chromosome Chromosome, Telomeric Region Nuclear Telomere Cap Complex Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Body Mre11 Complex Shelterin Complex
	Molecular Function	DNA Binding Protein Binding	Protein Binding Phosphatase Binding Telomeric DNA Binding G-rich Strand Telomeric DNA Binding
	Biological Process	Chromatin Organization Cell Cycle Multicellular Organism Development Protein Localization To Nucleus Negative Regulation Of Protein Catabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Signal Transduction By P53 Class Mediator	Telomere Maintenance Negative Regulation Of Protein Phosphorylation Regulation Of Transcription, DNA-templated Telomere Maintenance Via Telomerase Regulation Of Double-strand Break Repair Via Homologous Recombination Telomere Maintenance Via Telomere Lengthening Telomere Capping Protection From Non-homologous End Joining At Telomere Regulation Of Telomere Maintenance Negative Regulation Of Telomere Maintenance Positive Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of DNA Recombination At Telomere Positive Regulation Of NF-kappaB Transcription Factor Activity Protein Localization To Chromosome, Telomeric Region Positive Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of Protein Acetylation
Pathways		Regulation of TP53 Activity through Association with Co-factors	Recognition and association of DNA glycosylase with site containing an affected pyrimidine Cleavage of the damaged pyrimidine Recognition and association of DNA glycosylase with site containing an affected purine Recognition and association of DNA glycosylase with site containing an affected purine Cleavage of the damaged purine Cleavage of the damaged purine Meiotic synapsis Packaging Of Telomere Ends Telomere Extension By Telomerase Polymerase switching on the C-strand of the telomere Processive synthesis on the C-strand of the telomere Telomere C-strand (Lagging Strand) Synthesis Telomere C-strand synthesis initiation Removal of the Flap Intermediate from the C-strand DNA Damage/Telomere Stress Induced Senescence Inhibition of DNA recombination at telomere
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Central corneal thickness ( 28171582 20719862) Corneal structure ( 23291589) HDL cholesterol levels ( 32203549) Intraocular pressure ( 29235454) Mean spheric corpuscular volume ( 32888494) Platelet count ( 32888494) Plateletcrit ( 32888494) Systolic blood pressure ( 30224653) Triglyceride levels ( 32203549)	Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Smoking status (ever vs never smokers) ( 30643258) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
Interacting Genes		194 interacting genes: ABLIM3 ADAM15 AFG1L ALAS2 ANAPC11 ANKRD55 ANTKMT ARID5A ATF2 ATXN7L2 BAG5 BICRAL BLZF1 BOC BTG3 C1orf94 C1QTNF2 C22orf15 C22orf39 C2orf83 C3orf36 C4orf45 CAMK2D CBX8 CCDC26 CCDC74B CDC7 CDSN CDX4 CEP76 CFAP206 CHRDL2 COL10A1 CRX CSNK2B CTSZ CYTOR DCDC2B DLX3 DNAJA4 ENKD1 EPHA10 ESM1 FAM117B FAM120C FAM217B FAM222B FAM71C FAM90A1 FARS2 FHL2 FHL5 FLOT1 FOXM1 FOXR1 GAS2L2 GFM2 GOLGA6L9 HAPLN2 HEYL HHIPL1 HIVEP1 HMGB3P1 HNRNPLL HSFY1 IDO2 IGF1 IGFN1 INO80B ISCU KCTD9 KHDC4 KLF15 KRTAP8-1 L3MBTL3 LAP3 LENG1 LGALS14 LGALS4 LHX4 LHX8 LIN54 LINC01547 LMO1 LMO2 LMO3 LMO4 LRIF1 LSM2 MAP2K1 MAPK1 MAX MDFI MEOX1 MEOX2 MIR4435-2HG MRPL28 MRRF MSRB3 MTERF4 MVP NEDD9 NFYA NMNAT1 NOTO NRIP2 PANX2 PARD6B PAX6 PHF21A PHF21B PID1 PIH1D2 PIK3C2G PIM1 PML PNRC2 POGZ POLDIP3 POLR2L POU6F2 PPIB PPIC PPIF PRDM6 PRKAB2 PRKCH PRPF39 PRR20A PRR20B PRR20C PRR20D PRR20E PRR23B PRR34 PSMD9 PSORS1C2 RAB3IP RAD54L2 RBM39 RBPMS REL RELA RHNO1 RHOH RHOQ RIDA RIMS3 RPP25 RYBP SAPCD1 SCN5A SH3RF2 SLC16A3 SNAPIN SNRPB SNX5 SP2 SP4 SPACA6 SPANXN2 SRARP STK38 STOX1 TAF6 TERF2 TERF2IP TNXB TOX TOX4 TP53 TRAF2 TRAF4 TRIM35 TROAP TTC23 UBAP2 UBE2I VEZF1 VMAC XAGE1B YJU2 ZBTB4 ZC2HC1C ZMIZ2 ZMYM6 ZNF410 ZNF438 ZNF471 ZNF474 ZNF488 ZNF512B ZNF580 ZNF581	128 interacting genes: ADA AIMP2 AK1 AKR1A1 AKR1B10 AKR7A3 AKT1 ANXA5 ANXA8L1 AP2B1 APEX1 ARPP21 BABAM1 BANP BCL7B C1orf174 C9orf78 CALML3 CHMP2B COTL1 CPNE2 CPNE3 CRK CRYBB1 CRYGS CTBP1 DBNL DDX23 DDX24 DDX39A DHX38 DNMT3A DPP3 ENAH EPAS1 EPS8L1 FABP2 GAGE5 GAMT GNMT GPKOW H1-1 H2AC16 H4C2 HAAO HAGH HDGFL3 HMGB1 HMGB3 HMGN3 HMGN4 HNRNPK IDO1 IL1RN LANCL2 LGALSL MAGOHB MCM2 MDH1 MPG MRTO4 MT1X MT3 NAIF1 NASP NOL3 NPSR1 NUDT14 NUDT18 NUMA1 NXNL1 OCM2 OGFR PABIR1 PACSIN2 PACSIN3 PAFAH1B3 PCNP PCP4 PEA15 PGLS PGM1 PML PNMT POLD1 PPM1G PPP1R2 PPP6R3 PRDX6 PRX PTEN PTMA RABIF RAD50 RASSF5 RBBP9 RECQL4 RGMA RIF1 RPAP1 RPP25 S100P SBDS SCLY SCRN2 SET SMARCC2 SNCG SP100 TALDO1 TBC1D10A TBCA TERF2 TMSB10 TMSB4Y TOR1AIP1 TSSC4 TWF2 UCHL1 VGLL4 WDR5 WIPI2 XAGE2 XPO1 XRCC5 XRCC6 ZNF146 ZNF414
Entrez ID		54971	54386
HPRD ID		16538	05452
Ensembl ID		ENSG00000172530	ENSG00000166848
Uniprot IDs		A0A0S2Z5C2 A0A0S2Z5G4 A0A0S2Z5M2 B3KM38 B4DE54 Q8N9N5 Q9NSS6	Q9NYB0
PDB IDs			1FEX 3K6G 4RQI
Enriched GO Terms of Interacting Partners?
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