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PTAFR and RGS4
Data Source:
HPRD
(in vitro)
PTAFR
RGS4
Description
platelet activating factor receptor
regulator of G protein signaling 4
Image
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
Membrane
Integral Component Of Membrane
Secretory Granule Membrane
Tertiary Granule Membrane
Nucleus
Cytoplasm
Cytosol
Plasma Membrane
Protein-containing Complex
Molecular Function
Lipopolysaccharide Binding
Lipopolysaccharide Immune Receptor Activity
G Protein-coupled Receptor Activity
Platelet Activating Factor Receptor Activity
Protein Binding
Phospholipid Binding
G Protein-coupled Purinergic Nucleotide Receptor Activity
Mitogen-activated Protein Kinase Binding
G-protein Alpha-subunit Binding
GTPase Activity
GTPase Activator Activity
Calmodulin Binding
Biological Process
Positive Regulation Of Cellular Extravasation
Regulation Of Transcription By RNA Polymerase II
Chemotaxis
Inflammatory Response
Immune Response
G Protein-coupled Receptor Signaling Pathway
Parturition
Response To Symbiotic Bacterium
Positive Regulation Of Phospholipase C Activity
Cytokine-mediated Signaling Pathway
Lipopolysaccharide-mediated Signaling Pathway
Positive Regulation Of Interleukin-6 Production
Positive Regulation Of Tumor Necrosis Factor Production
Inositol Trisphosphate Biosynthetic Process
G Protein-coupled Purinergic Nucleotide Receptor Signaling Pathway
Neutrophil Degranulation
Positive Regulation Of Neutrophil Degranulation
Transcytosis
Positive Regulation Of Translation
Negative Regulation Of Blood Pressure
Positive Regulation Of Vasoconstriction
Phosphatidylinositol-mediated Signaling
Positive Regulation Of Smooth Muscle Cell Proliferation
Interferon-gamma-mediated Signaling Pathway
Positive Regulation Of Inositol Phosphate Biosynthetic Process
Cellular Response To Gravity
Cellular Response To CAMP
Cellular Response To Fatty Acid
Response To Dexamethasone
Positive Regulation Of Voltage-gated Chloride Channel Activity
Positive Regulation Of Leukocyte Tethering Or Rolling
Positive Regulation Of Sensory Perception Of Pain
Positive Regulation Of Transcytosis
Positive Regulation Of Maternal Process Involved In Parturition
Positive Regulation Of Gastro-intestinal System Smooth Muscle Contraction
Cellular Response To 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine
Inactivation Of MAPK Activity
Response To Amphetamine
G Protein-coupled Receptor Signaling Pathway
Brain Development
Regulation Of G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Heart Rate
Response To Cocaine
Response To Morphine
Positive Regulation Of GTPase Activity
Response To Ethanol
Negative Regulation Of G Protein-coupled Receptor Signaling Pathway
Regulation Of Calcium Ion Transport
Negative Regulation Of Dopamine Receptor Signaling Pathway
Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development
Regulation Of Actin Filament Organization
Negative Regulation Of Glycine Import Across Plasma Membrane
Negative Regulation Of Potassium Ion Transmembrane Transport
Dorsal Root Ganglion Development
Positive Regulation Of Excitatory Postsynaptic Potential
Pathways
Class A/1 (Rhodopsin-like receptors)
G alpha (q) signalling events
Interleukin-10 signaling
Neutrophil degranulation
Interferon gamma signaling
G alpha (q) signalling events
G alpha (i) signalling events
G alpha (i) signalling events
G alpha (z) signalling events
Drugs
Platelet Activating Factor
Etizolam
Rupatadine
Diseases
GWAS
Blond vs. brown/black hair color (
30531825
)
Response to fenofibrate (triglyceride levels) (
27002377
)
Response to mTOR inhibitor (rapamycin) (
24009623
)
Interacting Genes
19 interacting genes:
ARR3
ARRB2
CALM1
GORAB
GRIN1
GTPBP3
IFITM3
MBP
MFSD3
PLLP
PPM1J
PRNP
RGS4
RHBDD2
SERINC5
SPATA24
TMEM120A
TMX2
TYK2
13 interacting genes:
CALM1
COPB1
COPB2
EGFR
ERBB3
GABBR1
GNAI1
GNAI2
GNAO1
GNAQ
KRIT1
PLCB1
PTAFR
Entrez ID
5724
5999
HPRD ID
01422
03947
Ensembl ID
ENSG00000169403
ENSG00000117152
Uniprot IDs
A8K7N8
P25105
A0A024R909
P49798
PDB IDs
2B0X
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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