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MAL2 and GJB1
Data Source:
BioGRID
(two hybrid)
MAL2
GJB1
Description
mal, T cell differentiation protein 2
gap junction protein beta 1
Image
No pdb structure
GO Annotations
Cellular Component
Endomembrane System
Integral Component Of Membrane
Apical Plasma Membrane
Membrane Raft
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Endoplasmic Reticulum Membrane
Connexin Complex
Integral Component Of Membrane
Molecular Function
Protein Binding
Structural Constituent Of Myelin Sheath
Gap Junction Channel Activity
Protein Binding
Biological Process
Myelination
Transcytosis
Cell-cell Signaling
Nervous System Development
Gap Junction Assembly
Transmembrane Transport
Pathways
Oligomerization of connexins into connexons
Oligomerization of connexins into connexons
Transport of connexins along the secretory pathway
Gap junction assembly
Drugs
Diseases
Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS
Blood pressure (smoking interaction) (
25189868
)
Gallstone disease (
30504769
)
Hippocampal atrophy (
19668339
)
Osteoprotegerin levels (
25080503
)
Interacting Genes
49 interacting genes:
ABCG8
AQP6
ARFIP2
ARL13B
ATP6V0E1
CD160
CD68
COQ8A
CREB3
CREB3L1
ECPAS
FAM3A
GAD1
GAD2
GJB1
GPR152
HSFX1
HSFX2
MRM1
MTERF3
MUC1
NDRG4
NFAM1
PBX3
PIMREG
PITPNC1
POLL
PPP1CA
PTPN9
RAB37
REEP4
RETREG3
S100B
SCN3B
SGK1
SH3GL1
SH3GLB1
SHMT2
SLC35C2
SUCLA2
TBRG4
THAP4
TMEM14B
TPD52
TPD52L1
TPD52L2
TTPA
TUBB
VARS2
57 interacting genes:
APOL3
APP
BMP10
C1GALT1
C2CD2L
C3orf52
CALM1
CD37
CD79A
CDIPT
CLEC7A
CMTM3
CMTM5
CNST
COMT
CTXN3
CXCL9
EFNA5
EGFR
EMP3
EPHA1
GJB2
GLP1R
GPR25
IER3IP1
ITGAM
LAT
LHFPL2
MAL
MAL2
MFF
MS4A13
MST1R
NDUFB11
NIPAL4
PRKACA
PRKCA
PTPN2
PTPN9
RTP2
SCD
SERTM1
SLC12A7
SRC
STX8
TEX264
TF
TM4SF4
TMEM120B
TMEM14C
TMEM19
TMEM218
TMEM98
UPK1B
VEGFA
VKORC1
YIPF6
Entrez ID
114569
2705
HPRD ID
14351
02367
Ensembl ID
ENSG00000147676
ENSG00000169562
Uniprot IDs
A0A024R9E4
Q969L2
A0A654ICJ7
P08034
PDB IDs
1TXH
5KK9
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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