MAL2 and TTPA

Data Source:
BioGRID (two hybrid)

		MAL2	TTPA
Description		mal, T cell differentiation protein 2	alpha tocopherol transfer protein
Image		No pdb structure
GO Annotations	Cellular Component	Endomembrane System Integral Component Of Membrane Apical Plasma Membrane Membrane Raft Perinuclear Region Of Cytoplasm Extracellular Exosome	Late Endosome Cytosol
	Molecular Function	Protein Binding Structural Constituent Of Myelin Sheath	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Vitamin E Binding Phosphatidylinositol-3,4-bisphosphate Binding Lipid Transfer Activity Phosphatidylinositol Bisphosphate Binding
	Biological Process	Myelination Transcytosis	Lipid Metabolic Process Response To Nutrient Response To PH Developmental Process Vitamin E Metabolic Process Vitamin Transport Intracellular PH Reduction Negative Regulation Of Cell Death Intermembrane Lipid Transfer
Pathways			Vitamin E
Drugs
Diseases			Ataxia with isolated vitamin E deficiency (AVED); Friedreich-like ataxia
GWAS		Blood pressure (smoking interaction) ( 25189868) Gallstone disease ( 30504769) Hippocampal atrophy ( 19668339) Osteoprotegerin levels ( 25080503)
Interacting Genes		49 interacting genes: ABCG8 AQP6 ARFIP2 ARL13B ATP6V0E1 CD160 CD68 COQ8A CREB3 CREB3L1 ECPAS FAM3A GAD1 GAD2 GJB1 GPR152 HSFX1 HSFX2 MRM1 MTERF3 MUC1 NDRG4 NFAM1 PBX3 PIMREG PITPNC1 POLL PPP1CA PTPN9 RAB37 REEP4 RETREG3 S100B SCN3B SGK1 SH3GL1 SH3GLB1 SHMT2 SLC35C2 SUCLA2 TBRG4 THAP4 TMEM14B TPD52 TPD52L1 TPD52L2 TTPA TUBB VARS2	46 interacting genes: AGTRAP APOA5 APOC2 APP ARFIP2 ARMC12 BIRC7 CISD2 CMTM4 CMTM5 COQ3 CYSRT1 DGAT2L6 DHODH FADS6 FAM114A2 FAM25A FAM25C FAM25G FGF14 FKBP7 GOLGA2 HSD17B11 JOSD2 KRTAP10-7 KRTAP12-2 KRTAP12-3 KRTAP2-3 KRTAP2-4 LEUTX MAL2 MRM1 NBPF19 NDUFA7 NOTCH2NLA PEX12 REEP2 RPRM SAR1A SCAMP1 SCAMP5 SDR16C5 SLC35E3 SYNGR3 THAP4 TPD52
Entrez ID		114569	7274
HPRD ID		14351	02685
Ensembl ID		ENSG00000147676	ENSG00000137561
Uniprot IDs		A0A024R9E4 Q969L2	P49638
PDB IDs			1OIP 1OIZ 1R5L 5MUE 5MUG
Enriched GO Terms of Interacting Partners?
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