CELF4 and TIAL1

Data Source:
BioGRID (two hybrid)

		CELF4	TIAL1
Description		CUGBP Elav-like family member 4	TIA1 cytotoxic granule associated RNA binding protein like 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Ribonucleoprotein Complex	Nucleus Nucleoplasm Cytoplasm Lysosome Cytoplasmic Stress Granule Ribonucleoprotein Complex
	Molecular Function	Translation Repressor Activity, MRNA Regulatory Element Binding RNA Binding MRNA Binding Pre-mRNA Binding BRE Binding	DNA Binding RNA Binding
	Biological Process	Alternative MRNA Splicing, Via Spliceosome Regulation Of Alternative MRNA Splicing, Via Spliceosome In Utero Embryonic Development MRNA Splice Site Selection Germ Cell Development Embryo Development Ending In Birth Or Egg Hatching Negative Regulation Of Translation Negative Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Excitatory Postsynaptic Potential Regulation Of Retina Development In Camera-type Eye	Regulation Of Transcription By RNA Polymerase II Apoptotic Process Defense Response Fibroblast Growth Factor Receptor Signaling Pathway
Pathways			FGFR2 alternative splicing
Drugs
Diseases
GWAS		Body fat mass ( 28552196) Chronotype ( 30696823) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Educational attainment ( 25201988) Experiencing mood swings ( 29500382) Feeling fed-up ( 29500382) Feeling guilty ( 29500382) Feeling hurt ( 29500382) Feeling miserable ( 29500382) General factor of neuroticism ( 30867560) Household income ( 31844048) Household income (MTAG) ( 31844048) Mood instability ( 31168069) Neurociticism ( 29500382) Neuroticism ( 27089181 27067015) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245) Refractive error ( 32231278) Worry too long after an embarrassing experience ( 29500382)	Depressive symptoms (stressful life events interaction) ( 27529621) Monocyte percentage of white cells ( 32888494) Parkinson's disease ( 27182965) Response to carboplatin and paclitaxel in ovarian cancer (MTT IC50) ( 27047539)
Interacting Genes		10 interacting genes: APP LYST PCBP3 PRR20A PRR20B PRR20C PRR20D PRR20E RBPMS2 TIAL1	39 interacting genes: AKAP8L AOC1 BPIFA1 C10orf55 CAMK2A CELF4 DAZAP2 FAM168A FAM168B FUBP1 GRINA INCA1 KLF1 KRTAP8-1 MAGED1 MAPK1 MAPK1IP1L MBNL2 MIR106A MIR106B MIR145 MIR199A1 MIR20A MIR29A MIR29C MIR34A MIR9-2 PRR13 PRR20A PRR20B PRR20C PRR20D PRR20E QKI RBPMS2 SMN1 SMN2 SNRPA VPS37C
Entrez ID		56853	7073
HPRD ID		12534	04563
Ensembl ID		ENSG00000101489	ENSG00000151923
Uniprot IDs		Q9BZC1	Q01085 Q49AS9
PDB IDs		2DGP 2DNK	1X4G 2CQI 2DH7
Enriched GO Terms of Interacting Partners?
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