PANX2 and NRF1

Data Source:
BioGRID (two hybrid)

		PANX2	NRF1
Description		pannexin 2	nuclear respiratory factor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Gap Junction Integral Component Of Membrane	Nucleus Nucleoplasm Cytosol Extracellular Exosome
	Molecular Function	Structural Molecule Activity Wide Pore Channel Activity Gap Junction Hemi-channel Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Protein Homodimerization Activity
	Biological Process	Response To Ischemia Cation Transport Cell-cell Signaling Positive Regulation Of Interleukin-1 Production Transmembrane Transport	Regulation Of Transcription By RNA Polymerase II Mitochondrion Organization Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Electric Transmission Across Gap Junctions	PPARA activates gene expression Transcriptional activation of mitochondrial biogenesis Transcriptional activation of mitochondrial biogenesis
Drugs
Diseases
GWAS		Acne (severe) ( 24927181)	Bipolar disorder ( 31043756) Obesity-related traits ( 23251661) Platelet count ( 27863252) Plateletcrit ( 27863252) Red cell distribution width ( 28957414) Response to antidepressants and depression ( 27622933)
Interacting Genes		3 interacting genes: ATXN1 BANP NRF1	48 interacting genes: AGR2 BBS2 BICRAL BRWD1 C10orf55 C3orf36 CKMT2 COL10A1 CSNK2A1 CSNK2B DYNLL1 ESM1 FHL2 HHIPL1 HIVEP1 KHDC4 KLF15 KPNA5 KRT83 L3MBTL2 L3MBTL3 LHX3 LHX4 LHX6 LMO4 MAFF MVP NDUFAB1 PANX2 PARP1 PLXDC1 POGZ PPARGC1A PPRC1 SIAH2 SLC22A18AS SP2 SP4 SPSB2 SRARP TESMIN TEX43 TOLLIP TRAF2 TRIM35 VEZF1 YPEL3 ZMYM6
Entrez ID		56666	4899
HPRD ID		09760	02930
Ensembl ID		ENSG00000073150	ENSG00000106459
Uniprot IDs		B3KTT7 Q495U3 Q96RD6	A0A024R770 A0A024R774 Q16656
PDB IDs
Enriched GO Terms of Interacting Partners?
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