NRF1 and C3orf36

Data Source:
BioGRID (two hybrid)

		NRF1	C3orf36
Description		nuclear respiratory factor 1	chromosome 3 putative open reading frame 36
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Extracellular Exosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Protein Homodimerization Activity	Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Mitochondrion Organization Positive Regulation Of Transcription By RNA Polymerase II
Pathways		PPARA activates gene expression Transcriptional activation of mitochondrial biogenesis Transcriptional activation of mitochondrial biogenesis
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Obesity-related traits ( 23251661) Platelet count ( 27863252) Plateletcrit ( 27863252) Red cell distribution width ( 28957414) Response to antidepressants and depression ( 27622933)
Interacting Genes		48 interacting genes: AGR2 BBS2 BICRAL BRWD1 C10orf55 C3orf36 CKMT2 COL10A1 CSNK2A1 CSNK2B DYNLL1 ESM1 FHL2 HHIPL1 HIVEP1 KHDC4 KLF15 KPNA5 KRT83 L3MBTL2 L3MBTL3 LHX3 LHX4 LHX6 LMO4 MAFF MVP NDUFAB1 PANX2 PARP1 PLXDC1 POGZ PPARGC1A PPRC1 SIAH2 SLC22A18AS SP2 SP4 SPSB2 SRARP TESMIN TEX43 TOLLIP TRAF2 TRIM35 VEZF1 YPEL3 ZMYM6	23 interacting genes: ANKS1A APP BANP HDAC7 HGS MAP2K5 NRF1 PIK3R3 PIN1 PPP1R16A PPP2CA PRKAB2 PRR20A PRR20B PRR20C PRR20D PRR20E RIPPLY2 TENT5B TRIM55 TRIM63 UBTFL1 ZNF76
Entrez ID		4899	80111
HPRD ID		02930	07981
Ensembl ID		ENSG00000106459	ENSG00000288547
Uniprot IDs		A0A024R770 A0A024R774 Q16656
PDB IDs
Enriched GO Terms of Interacting Partners?
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