NRF1 and BICRAL

Data Source:
BioGRID (two hybrid)

		NRF1	BICRAL
Description		nuclear respiratory factor 1	BRD4 interacting chromatin remodeling complex associated protein like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Extracellular Exosome	SWI/SNF Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Protein Homodimerization Activity	Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Mitochondrion Organization Positive Regulation Of Transcription By RNA Polymerase II	Positive Regulation Of Transcription, DNA-templated
Pathways		PPARA activates gene expression Transcriptional activation of mitochondrial biogenesis Transcriptional activation of mitochondrial biogenesis
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Obesity-related traits ( 23251661) Platelet count ( 27863252) Plateletcrit ( 27863252) Red cell distribution width ( 28957414) Response to antidepressants and depression ( 27622933)
Interacting Genes		48 interacting genes: AGR2 BBS2 BICRAL BRWD1 C10orf55 C3orf36 CKMT2 COL10A1 CSNK2A1 CSNK2B DYNLL1 ESM1 FHL2 HHIPL1 HIVEP1 KHDC4 KLF15 KPNA5 KRT83 L3MBTL2 L3MBTL3 LHX3 LHX4 LHX6 LMO4 MAFF MVP NDUFAB1 PANX2 PARP1 PLXDC1 POGZ PPARGC1A PPRC1 SIAH2 SLC22A18AS SP2 SP4 SPSB2 SRARP TESMIN TEX43 TOLLIP TRAF2 TRIM35 VEZF1 YPEL3 ZMYM6	25 interacting genes: ARHGDIG ATXN1 BANP BFSP2 CACHD1 CDC5L DTNBP1 DTX2 EXOC8 FNDC3B HGS HSPB2 HSPB2-C11orf52 NFYC NGLY1 NRF1 PRR20A PRR20B PRR20C PRR20D PRR20E QRICH1 SS18L1 TRIM23 USHBP1
Entrez ID		4899	23506
HPRD ID		02930	17180
Ensembl ID		ENSG00000106459	ENSG00000112624
Uniprot IDs		A0A024R770 A0A024R774 Q16656	Q6AI39
PDB IDs
Enriched GO Terms of Interacting Partners?
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