Description |
presenilin 1 |
dedicator of cytokinesis 3 |
Image |
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No pdb structure |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
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- Asthma ( 32296059)
- Bacteremia ( 27236921)
- Blood protein levels ( 28240269)
- Body fat distribution (arm fat ratio) ( 30664634)
- Body fat distribution (trunk fat ratio) ( 30664634)
- Body fat mass ( 28552196)
- Brain morphology (min-P) ( 32665545)
- Brain morphology (MOSTest) ( 32665545)
- Cholangiocarcinoma in primary sclerosing cholangitis (time to event) ( 28779025)
- Cocaine dependence ( 31212010)
- Colorectal cancer ( 29228715)
- Cortical surface area (MOSTest) ( 32665545)
- Depressive symptom (appetite changes) (binary trait) ( 31530331)
- Depressive symptoms (binary sum-score) ( 31530331)
- Depressive symptoms (sum-score) ( 31530331)
- Eosinophil counts ( 32888494 27863252)
- Eosinophil percentage of granulocytes ( 27863252)
- Eosinophil percentage of white cells ( 32888494 27863252)
- Estimated glomerular filtration rate ( 31152163)
- Height ( 20881960 25282103)
- Melanoma ( 24980573)
- Morning person ( 30696823)
- Refractive error ( 32231278)
- Subcortical volume (min-P) ( 32665545)
- Subcortical volume (MOSTest) ( 32665545)
- Sum eosinophil basophil counts ( 27863252)
- Trunk fat mass ( 28552196)
- Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
- Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
- Waist circumference adjusted for BMI in non-smokers ( 28443625)
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Interacting Genes |
92 interacting genes:
ACTN1
AP1M2
APBA1
APH1A
APH1B
APOE
APP
BACE1
BCL2
BCL2L1
CASP1
CASP3
CASP4
CASP6
CASP7
CASP8
CDH1
CDK5
CFL1
CIB1
CTNNA1
CTNNB1
CTNND1
CTNND2
CYP2C18
CYP2C8
DLL1
DOCK3
ECSIT
EFHD1
EFNB2
ENSA
EPB41L3
ERN1
ETFA
FBXL12
FBXW7
FGF13
FLNA
FLNB
GAPDH
GCDH
GDI1
GFAP
GSK3B
HERPUD1
HMGB1
ICAM5
ITSN2
JUP
KANK2
KCNIP3
KCNIP4
MAPK9
MAPT
METTL2B
MTCH1
NCSTN
NOS3
NOTCH1
NOTCH2
NOTCH3
NOTCH4
OXCT1
PDCD4
PIK3R1
PKP4
PRAM1
PRDX2
PRKACA
PRKCZ
PSENEN
PSMA5
PSMB1
RAB11A
RAB3A
RAD23A
RHEB
RMDN3
RNF32
RYR2
SCAF11
SCN1A
SLC10A6
ST13
STAMBPL1
TCF7L2
TDP2
TUBA1B
UBQLN1
UMPS
YME1L1
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10 interacting genes:
CALM1
CRK
HOXA1
KHDRBS1
NR3C1
PLEKHF2
PSEN1
PSEN2
RAC1
SRPK2
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Entrez ID |
5663 |
1795 |
HPRD ID |
00087 |
10341 |
Ensembl ID |
ENSG00000080815
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ENSG00000088538
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Uniprot IDs |
A0A024R6A3
A0A0S2Z4D2
P49768
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Q8IZD9
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PDB IDs |
2KR6
4UIS
5A63
5FN2
5FN3
5FN4
5FN5
6IDF
6IYC
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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