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MASP1 and NUDT21
Data Source:
BioGRID
(two hybrid)
MASP1
NUDT21
Description
MBL associated serine protease 1
nudix hydrolase 21
Image
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Nucleoplasm
Cytosol
Nucleus
Nucleoplasm
Cytoplasm
Centrosome
MRNA Cleavage And Polyadenylation Specificity Factor Complex
MRNA Cleavage Factor Complex
Nuclear Body
Centriolar Satellite
Paraspeckles
Molecular Function
Serine-type Endopeptidase Activity
Calcium Ion Binding
Protein Binding
Peptidase Activity
Protein Homodimerization Activity
Calcium-dependent Protein Binding
Chromatin Binding
RNA Binding
MRNA Binding
Protein Binding
Hydrolase Activity
MRNA 3'-UTR AU-rich Region Binding
Identical Protein Binding
Protein Homodimerization Activity
Histone Deacetylase Binding
Biological Process
Complement Activation, Lectin Pathway
Proteolysis
Receptor-mediated Endocytosis
Complement Activation
MRNA Splicing, Via Spliceosome
Termination Of RNA Polymerase II Transcription
MRNA Polyadenylation
MRNA Processing
Posttranscriptional Regulation Of Gene Expression
Cell Differentiation
MRNA 3'-end Processing
Positive Regulation Of MRNA Cleavage
Protein Tetramerization
Protein Heterotetramerization
Pre-mRNA Cleavage Required For Polyadenylation
MRNA Alternative Polyadenylation
Positive Regulation Of MRNA Polyadenylation
Messenger Ribonucleoprotein Complex Assembly
Positive Regulation Of Stem Cell Differentiation
Positive Regulation Of Pro-B Cell Differentiation
Pathways
Lectin pathway of complement activation
Initial triggering of complement
Ficolins bind to repetitive carbohydrate structures on the target cell surface
Scavenging by Class A Receptors
mRNA Splicing - Major Pathway
mRNA 3'-end processing
RNA Polymerase II Transcription Termination
Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS
Amyotrophic lateral sclerosis (sporadic) (
24529757
)
Blood protein levels (
30072576
)
Impulsivity (attentional) (
30718321
)
Type 2 diabetes (
30130595
)
Interacting Genes
16 interacting genes:
C2
C3
FCN2
GADD45A
GSK3B
H2AX
MAPK6
MAPK8IP2
MAPT
MBL2
NCK2
NUDT21
RPS6KA3
RPS6KA6
SERPING1
UFD1
119 interacting genes:
A2M
ATXN1
CARM1
CDC42
CEP126
CLP1
CPSF6
CPSF7
CTNND2
DBN1
DNMT3L
DYNC1I1
EED
EEF1G
ESR1
EXOSC6
F13A1
FAM90A1
FBN3
FLAD1
FUNDC2
GOLGA2
HSF4
IKZF1
ITCH
JMJD1C
KIFAP3
KRT75
MASP1
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-2
MIR138-1
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200B
MIR205
MIR206
MIR20A
MIR214
MIR221
MIR25
MIR29A
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-2
MIR9-2
MIR92A1
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
MYL6
NEDD4
NGEF
NIF3L1
NTAQ1
POLR2C
PSMF1
PSPC1
PTN
PYCR1
RBM48
RCC1
RNF19A
RPLP1
S100PBP
SEM1
SEMA5B
SF3B1
SHC1
SLC44A1
SNCAIP
SNRNP70
SPAG8
SRPK1
TCERG1
TEPSIN
TLE1
TRA2A
TRIM23
TRIM27
WWOX
ZNF655
ZRANB1
Entrez ID
5648
11051
HPRD ID
02749
05400
Ensembl ID
ENSG00000127241
ENSG00000167005
Uniprot IDs
F8W876
P48740
A0A024R6W2
O43809
PDB IDs
3DEM
3GOV
4AQB
4DJZ
4IGD
4IW4
4KKD
2CL3
2J8Q
3BAP
3BHO
3MDG
3MDI
3N9U
3P5T
3P6Y
3Q2S
3Q2T
5R4P
5R4Q
5R4R
5R4S
5R4T
5R4U
5R64
5R65
5R66
5R67
Enriched GO Terms of Interacting Partners
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