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CRCP and VAV2
Data Source:
BioGRID
(two hybrid)
CRCP
VAV2
Description
CGRP receptor component
vav guanine nucleotide exchange factor 2
Image
No pdb structure
GO Annotations
Cellular Component
Acrosomal Vesicle
Nucleoplasm
RNA Polymerase III Complex
Cytosol
Plasma Membrane
DNA Polymerase III Complex
Cytosol
Plasma Membrane
Molecular Function
Nucleotide Binding
Calcitonin Gene-related Peptide Receptor Activity
DNA-directed 5'-3' RNA Polymerase Activity
Protein Binding
Phosphotyrosine Residue Binding
Guanyl-nucleotide Exchange Factor Activity
Epidermal Growth Factor Receptor Binding
Protein Binding
Metal Ion Binding
Biological Process
Transcription By RNA Polymerase III
Transcription Initiation From RNA Polymerase III Promoter
Neuropeptide Signaling Pathway
Positive Regulation Of Type I Interferon Production
Innate Immune Response
Defense Response To Virus
Angiogenesis
Signal Transduction
G Protein-coupled Receptor Signaling Pathway
Small GTPase Mediated Signal Transduction
Regulation Of Cell Size
Cell Migration
Lamellipodium Assembly
Platelet Activation
Fc-epsilon Receptor Signaling Pathway
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Positive Regulation Of Apoptotic Process
Regulation Of GTPase Activity
Positive Regulation Of Phosphatidylinositol 3-kinase Activity
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Ephrin Receptor Signaling Pathway
Regulation Of Small GTPase Mediated Signal Transduction
Pathways
Cytosolic sensors of pathogen-associated DNA
RNA Polymerase III Chain Elongation
RNA Polymerase III Transcription Termination
RNA Polymerase III Abortive And Retractive Initiation
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
GPVI-mediated activation cascade
GPVI-mediated activation cascade
NRAGE signals death through JNK
Rho GTPase cycle
Regulation of actin dynamics for phagocytic cup formation
DAP12 signaling
FCERI mediated MAPK activation
FCERI mediated Ca+2 mobilization
FCERI mediated Ca+2 mobilization
EPH-ephrin mediated repulsion of cells
G alpha (12/13) signalling events
VEGFA-VEGFR2 Pathway
VEGFA-VEGFR2 Pathway
Signal transduction by L1
VEGFR2 mediated vascular permeability
FCGR3A-mediated phagocytosis
FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS
Aortic root size (
21223598
)
Estimated glomerular filtration rate (
31152163
)
Central corneal thickness (
29760442
)
Corneal astigmatism (
30306274
)
Gut microbiota (bacterial taxa, hurdle binary method) (
32572223
)
Hematocrit (
27863252
)
Hemoglobin concentration (
27863252
)
Hemoglobin levels (
32327693
)
Multiple sclerosis (
20598377
)
Pre-treatment viral load in HIV-1 infection (
31219150
)
Red blood cell count (
32888494
)
vWF and FVIII levels (
21810271
)
Interacting Genes
9 interacting genes:
AGR2
CALCRL
DYNLRB1
GSC2
LRIF1
POLR3H
TCF12
VAV2
ZMIZ2
66 interacting genes:
AR
ARIH1
BIRC6
BOD1L1
BRDT
BZW1
CAV1
CBL
CBLB
CCNO
CCT2
CCT3
CD19
CD44
CEP170
CHMP3
CRCP
DCUN1D4
DNAJC21
EGFR
EIF4G3
EPHB2
ERBB2
ERBB3
ERBB4
FNTA
FUCA1
FYN
GAB1
GAPVD1
GRB2
HNRNPF
HSPH1
IPO4
MED21
MET
MRGBP
NCKAP5
NEK3
PHF10
PNMA1
POGZ
PPM1B
PRLR
RAC1
RAD23A
RBBP6
RHOA
RHOG
SERBP1
SF3A3
SH3BP2
SNW1
SOCS1
SRPK2
SRRT
ST13
STK24
SYK
TARBP2
TCP11
TOM1L1
TTN
UBE4B
USP38
VCPIP1
Entrez ID
27297
7410
HPRD ID
12089
02694
Ensembl ID
ENSG00000241258
ENSG00000160293
Uniprot IDs
A0A024RDL0
O75575
P52735
PDB IDs
2DLZ
2DM1
2LNW
2LNX
4ROJ
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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