EXOC7 and ARPC1A

Data Source:
HPRD (in vivo, in vitro)

		EXOC7	ARPC1A
Description		exocyst complex component 7	actin related protein 2/3 complex subunit 1A
Image		No pdb structure
GO Annotations	Cellular Component	Exocyst Microtubule Organizing Center Cytosol Plasma Membrane Membrane Growth Cone Membrane Centriolar Satellite Flemming Body	Nucleus Cytosol Arp2/3 Protein Complex Actin Cytoskeleton Site Of Double-strand Break Extracellular Exosome
	Molecular Function	Protein Binding	Actin Binding Actin Filament Binding
	Biological Process	Exocytosis Protein Transport Regulation Of Macroautophagy Regulation Of Entry Of Bacterium Into Host Cell	Actin Cytoskeleton Organization Arp2/3 Complex-mediated Actin Nucleation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Ephrin Receptor Signaling Pathway Membrane Organization
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium	Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation EPHB-mediated forward signaling RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs Clathrin-mediated endocytosis FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654)	Alcohol consumption ( 31358974) Dehydroepiandrosterone sulphate levels ( 21533175) Facial emotion recognition (sad faces) ( 28608620) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Medication use (calcium channel blockers) ( 31015401) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Serum metabolite levels ( 23093944) Ticagrelor levels in individuals with acute coronary syndromes treated with ticagrelor ( 25935875)
Interacting Genes		37 interacting genes: AKTIP ARFGEF2 ARPC1A BBS1 BBS2 BBS4 CCDC85B CCHCR1 CDC5L CT55 DISC1 DLG3 EXOC2 EXOC4 FBXO28 GRIN2B HGS IFT20 KDM1A KIFC3 KXD1 MSGN1 PLEKHF2 PRPF19 RALA RALY RHOQ RTN4IP1 SAPCD2 SMARCE1 SNAPIN SSC5D TRAF4 TRIM54 USHBP1 YAE1 ZC3H14	2 interacting genes: ERCC6 EXOC7
Entrez ID		23265	10552
HPRD ID		16292	07252
Ensembl ID		ENSG00000182473	ENSG00000241685
Uniprot IDs		B4DJ07 B5MCY9 Q63HP7 Q9UPT5	Q92747 V9HVZ6
PDB IDs			6YW7
Enriched GO Terms of Interacting Partners?
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