MED29 and USP47

Data Source:
HPRD (in vitro)

		MED29	USP47
Description		mediator complex subunit 29	ubiquitin specific peptidase 47
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mediator Complex	Nucleus Nucleoplasm Cytoplasm Cytosol SCF Ubiquitin Ligase Complex
	Molecular Function	Transcription Coregulator Activity Protein Binding Transcription Factor Binding	Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding WD40-repeat Domain Binding Ubiquitinyl Hydrolase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Base-excision Repair Ubiquitin-dependent Protein Catabolic Process Cellular Response To DNA Damage Stimulus Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Protein Deubiquitination Protein Phosphopantetheinylation Positive Regulation Of Cell Growth Regulation Of Protein Stability Cellular Response To UV Monoubiquitinated Protein Deubiquitination Response To Drug Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Pathways		PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation	Ub-specific processing proteases
Drugs
Diseases
GWAS			Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		13 interacting genes: ABI2 ABI3 BCAS2 EIF2B1 MED12 MED13 MED14 MED20 MED21 MED9 NRDE2 SSC5D USP47	6 interacting genes: AP4M1 MED29 MED9 PLA2G2A SNCA UBC
Entrez ID		55588	55031
HPRD ID		13748	11668
Ensembl ID		ENSG00000063322	ENSG00000170242
Uniprot IDs		B4DUA7 Q9NX70	Q68D97 Q96K76
PDB IDs
Enriched GO Terms of Interacting Partners?
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