USP47 and MED29

Data Source:
HPRD (in vitro)

		USP47	MED29
Description		ubiquitin specific peptidase 47	mediator complex subunit 29
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol SCF Ubiquitin Ligase Complex	Nucleoplasm Mediator Complex
	Molecular Function	Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding WD40-repeat Domain Binding Ubiquitinyl Hydrolase Activity	Transcription Coregulator Activity Protein Binding Transcription Factor Binding
	Biological Process	Base-excision Repair Ubiquitin-dependent Protein Catabolic Process Cellular Response To DNA Damage Stimulus Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Protein Deubiquitination Protein Phosphopantetheinylation Positive Regulation Of Cell Growth Regulation Of Protein Stability Cellular Response To UV Monoubiquitinated Protein Deubiquitination Response To Drug Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage	Regulation Of Transcription By RNA Polymerase II
Pathways		Ub-specific processing proteases	PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		6 interacting genes: AP4M1 MED29 MED9 PLA2G2A SNCA UBC	13 interacting genes: ABI2 ABI3 BCAS2 EIF2B1 MED12 MED13 MED14 MED20 MED21 MED9 NRDE2 SSC5D USP47
Entrez ID		55031	55588
HPRD ID		11668	13748
Ensembl ID		ENSG00000170242	ENSG00000063322
Uniprot IDs		Q68D97 Q96K76	B4DUA7 Q9NX70
PDB IDs
Enriched GO Terms of Interacting Partners?
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