MED29 and EIF2B1

Data Source:
BioGRID (two hybrid)

		MED29	EIF2B1
Description		mediator complex subunit 29	eukaryotic translation initiation factor 2B subunit alpha
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mediator Complex	Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 2B Complex Plasma Membrane Membrane
	Molecular Function	Transcription Coregulator Activity Protein Binding Transcription Factor Binding	Translation Initiation Factor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding Identical Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Translational Initiation Regulation Of Translational Initiation Response To Heat Response To Glucose Oligodendrocyte Development Response To Peptide Hormone Regulation Of Catalytic Activity T Cell Receptor Signaling Pathway
Pathways		PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation	Recycling of eIF2:GDP
Drugs
Diseases			Leukoencephalopathy with vanishing white matter; Vanishing white matter disease; Childhood ataxia with diffuse central nervous system hypomyelination (CACH); Cree leukoencephalopathy (CLE)
GWAS			Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		13 interacting genes: ABI2 ABI3 BCAS2 EIF2B1 MED12 MED13 MED14 MED20 MED21 MED9 NRDE2 SSC5D USP47	21 interacting genes: ADRA2A ADRA2B ADRA2C ADRB2 ARL4D ATF5 BZW2 C1orf50 CREBBP EIF2B2 EIF2S1 EIF2S2 EPM2A GORASP2 MED29 MRPL4 NTAQ1 RD3 TRIM59 TRIML2 UBE2I
Entrez ID		55588	1967
HPRD ID		13748	09458
Ensembl ID		ENSG00000063322	ENSG00000111361
Uniprot IDs		B4DUA7 Q9NX70	Q14232
PDB IDs			3ECS 6CAJ 6EZO 6K71 6K72 6O81 6O85 6O9Z
Enriched GO Terms of Interacting Partners?
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