USP47 and MED9

Data Source:
HPRD (in vitro)

		USP47	MED9
Description		ubiquitin specific peptidase 47	mediator complex subunit 9
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol SCF Ubiquitin Ligase Complex	Mediator Complex
	Molecular Function	Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding WD40-repeat Domain Binding Ubiquitinyl Hydrolase Activity	Transcription Coregulator Activity Protein Binding
	Biological Process	Base-excision Repair Ubiquitin-dependent Protein Catabolic Process Cellular Response To DNA Damage Stimulus Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Protein Deubiquitination Protein Phosphopantetheinylation Positive Regulation Of Cell Growth Regulation Of Protein Stability Cellular Response To UV Monoubiquitinated Protein Deubiquitination Response To Drug Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage	Regulation Of Transcription By RNA Polymerase II
Pathways		Ub-specific processing proteases	PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		Waist circumference adjusted for body mass index ( 28552196)	Birth weight ( 31043758) Estimated glomerular filtration rate ( 31152163)
Interacting Genes		6 interacting genes: AP4M1 MED29 MED9 PLA2G2A SNCA UBC	26 interacting genes: APP CBX4 CDK8 MED1 MED11 MED12 MED13 MED14 MED16 MED18 MED19 MED22 MED23 MED24 MED25 MED26 MED27 MED28 MED29 MED30 MED31 MED4 MED6 MED7 MED8 USP47
Entrez ID		55031	55090
HPRD ID		11668	14383
Ensembl ID		ENSG00000170242	ENSG00000141026
Uniprot IDs		Q68D97 Q96K76	Q9NWA0
PDB IDs
Enriched GO Terms of Interacting Partners?
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