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FEM1A and PTGER4
Data Source:
BioGRID
(affinity chromatography technology, two hybrid)
FEM1A
PTGER4
Description
fem-1 homolog A
prostaglandin E receptor 4
Image
No pdb structure
GO Annotations
Cellular Component
Ubiquitin Ligase Complex
Cytosol
Plasma Membrane
Integral Component Of Membrane
Molecular Function
Protein Binding
EP4 Subtype Prostaglandin E2 Receptor Binding
Prostaglandin E Receptor Activity
Protein Binding
Biological Process
Ubiquitin-dependent Protein Catabolic Process
Protein Ubiquitination
Post-translational Protein Modification
Negative Regulation Of Inflammatory Response
Regulation Of Ubiquitin-protein Transferase Activity
Negative Regulation Of Cytokine Production
Positive Regulation Of Cytokine Production
Inflammatory Response
Immune Response
G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Cytosolic Calcium Ion Concentration
JNK Cascade
Response To Mechanical Stimulus
Regulation Of Ossification
Response To Lipopolysaccharide
Negative Regulation Of Integrin Activation
T-helper Cell Differentiation
Negative Regulation Of Inflammatory Response
Positive Regulation Of Inflammatory Response
Regulation Of Stress Fiber Assembly
Bone Development
ERK1 And ERK2 Cascade
Cellular Response To Mechanical Stimulus
Cellular Response To Prostaglandin E Stimulus
Negative Regulation Of Eosinophil Extravasation
Pathways
Neddylation
Prostanoid ligand receptors
G alpha (s) signalling events
ADORA2B mediated anti-inflammatory cytokines production
Drugs
Dinoprostone
Misoprostol
Limaprost
Castor oil
Grapiprant
Diseases
GWAS
Height (
31562340
)
Allergic disease (asthma, hay fever or eczema) (
29083406
)
Ankylosing spondylitis (
23749187
21743469
)
Blood urea nitrogen levels (
31152163
)
Colorectal cancer or advanced adenoma (
30510241
)
Crohn's disease (
18587394
17684544
22936669
22412388
26278503
21102463
)
Gastric cancer (
22037551
26098866
)
Inflammatory bowel disease (
23128233
)
Multiple sclerosis (
19525953
21833088
22570697
28445677
)
Pediatric autoimmune diseases (
26301688
)
Red blood cell count (
32888494
)
Selective IgA deficiency (
27723758
)
Self-reported allergy (
23817569
)
Serum urea levels (
30808845
)
Ulcerative colitis (
21297633
)
Interacting Genes
11 interacting genes:
ACAA1
GOLGA6L9
INCA1
KIFC3
MALT1
MYOM3
NDUFAB1
OGFOD1
PPM1F
PTGER4
WWOX
42 interacting genes:
ACTN4
ACY3
ANAPC7
ATXN10
BIN1
BNIP1
CDPF1
CFAP298
CRADD
CRY2
CTNND2
DPF1
DST
EHMT2
FEM1A
GJC2
HMOX1
HMOX2
HOPX
KLC1
NISCH
NUBP2
NUP153
PDLIM1
PMPCB
PPP1R3F
PRDX1
PSMC1
PTPRA
RNF220
RTF2
SLBP
SLC39A8
SND1
SPP1
ST13
SUGT1
TMEM161A
TRAP1
VSTM2A
WDR19
ZNF337
Entrez ID
55527
5734
HPRD ID
16888
03350
Ensembl ID
ENSG00000141965
ENSG00000171522
Uniprot IDs
Q9BSK4
A0PJF5
P35408
PDB IDs
5YHL
5YWY
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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