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SRGN and SGTB
Data Source:
BioGRID
(two hybrid)
SRGN
SGTB
Description
serglycin
small glutamine rich tetratricopeptide repeat co-chaperone beta
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Golgi Apparatus
Secretory Granule
Platelet Alpha Granule Lumen
Mast Cell Granule
Schaffer Collateral - CA1 Synapse
Glutamatergic Synapse
Postsynaptic Specialization, Intracellular Component
Membrane
TRC Complex
Molecular Function
Protein Binding
Protein Binding
Molecular Adaptor Activity
Biological Process
Negative Regulation Of Cytokine Production
Platelet Degranulation
Apoptotic Process
Protein Processing
Negative Regulation Of Bone Mineralization
Biomineral Tissue Development
Secretory Granule Organization
Mast Cell Secretory Granule Organization
T Cell Secretory Granule Organization
Maintenance Of Protease Location In Mast Cell Secretory Granule
Maintenance Of Granzyme B Location In T Cell Secretory Granule
Modulation Of Chemical Synaptic Transmission
Regulation Of Postsynapse Organization
Granzyme-mediated Programmed Cell Death Signaling Pathway
Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane
Ubiquitin-dependent ERAD Pathway
Positive Regulation Of Chaperone-mediated Protein Folding
Pathways
Platelet degranulation
Drugs
Diseases
GWAS
Glycemic traits (pregnancy) (
23903356
)
Hemoglobin levels (
32327693
)
Brain morphology (MOSTest) (
32665545
)
Cortical surface area (MOSTest) (
32665545
)
Subcortical volume (MOSTest) (
32665545
)
Interacting Genes
17 interacting genes:
ALB
BAG6
CCL3
CD44
CEP70
FHL3
GZMB
NCALD
PEX12
PF4
PSRC1
SGTA
SGTB
UBQLN1
UBQLN2
UBQLN4
UBR4
116 interacting genes:
ABCG4
ADAT2
ADIPOQ
AGR2
AGR3
ASPH
BTC
C1QA
C1QL4
C1QTNF5
C1QTNF6
C5orf46
CALR
CCL3L3
CD200R1
CD3D
CD68
CD79B
CD99L2
CDH15
CDSN
CMPK1
COL10A1
COL1A2
COLQ
COMP
CREB3L3
CSH1
CSH2
CTAG1A
CTAG1B
CYB5R1
DEFA6
DEXI
DMKN
ECM1
EFEMP2
EMCN
ERP29
ETNK1
EVA1A
FBN1
FGF21
FZD7
GALNT11
GGH
GIP
GPX7
GYPA
HSP90B1
HSPA13
IL6R
IL6ST
ITPRIP
ITPRIPL1
KCNE5
KRT1
LAMP3
LAT
LCN2
LHB
LMO2
MYDGF
NAXD
NME3
OSMR
PAGE3
PDIA6
PGRMC1
PODXL
PPIB
PPIC
PRAP1
PRB1
PRB3
PRB4
PRR4
PSORS1C2
RAI2
RCN1
RNASE10
RNF144A
RNF144B
RNF170
SDC4
SDF2L1
SELENOM
SERPINE1
SERPINF1
SERPINI2
SGCA
SGTA
SHISA5
SIL1
SLPI
SOD3
SPINK4
SPP1
SRGN
SYT11
SYT4
TFF1
TMEM108
TMEM123
TMPO
TMUB1
TNFRSF19
TNFSF13
TXNDC12
UBL4A
UPK3A
VEGFC
VWC2
WFDC12
ZG16
ZG16B
Entrez ID
5552
54557
HPRD ID
01513
18049
Ensembl ID
ENSG00000122862
ENSG00000197860
Uniprot IDs
P10124
Q96EQ0
PDB IDs
Enriched GO Terms of Interacting Partners
?
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Tagcloud (Difference)
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Tagcloud (Intersection)
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