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SGTB and LCN2
Data Source:
BioGRID
(two hybrid)
SGTB
LCN2
Description
small glutamine rich tetratricopeptide repeat co-chaperone beta
lipocalin 2
Image
No pdb structure
GO Annotations
Cellular Component
Membrane
TRC Complex
Extracellular Region
Extracellular Space
Specific Granule Lumen
Extracellular Exosome
Molecular Function
Protein Binding
Molecular Adaptor Activity
Iron Ion Binding
Protein Binding
Small Molecule Binding
Identical Protein Binding
Enterobactin Binding
Biological Process
Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane
Ubiquitin-dependent ERAD Pathway
Positive Regulation Of Chaperone-mediated Protein Folding
Cellular Iron Ion Homeostasis
Apoptotic Process
Siderophore Transport
Cytokine-mediated Signaling Pathway
Antimicrobial Humoral Response
Defense Response To Bacterium
Neutrophil Degranulation
Innate Immune Response
Sequestering Of Iron Ion
Positive Regulation Of Cold-induced Thermogenesis
Pathways
Interleukin-4 and Interleukin-13 signaling
Neutrophil degranulation
Metal sequestration by antimicrobial proteins
Iron uptake and transport
Iron uptake and transport
Drugs
Methyl nonanoate
2,3-Dihydroxy-Benzoic Acid
Carboxymycobactin S
2,3,-Dihydroxybenzoylserine
Carboxymycobactin T
Trencam-3,2-Hopo
Diseases
GWAS
Brain morphology (MOSTest) (
32665545
)
Cortical surface area (MOSTest) (
32665545
)
Subcortical volume (MOSTest) (
32665545
)
Interacting Genes
116 interacting genes:
ABCG4
ADAT2
ADIPOQ
AGR2
AGR3
ASPH
BTC
C1QA
C1QL4
C1QTNF5
C1QTNF6
C5orf46
CALR
CCL3L3
CD200R1
CD3D
CD68
CD79B
CD99L2
CDH15
CDSN
CMPK1
COL10A1
COL1A2
COLQ
COMP
CREB3L3
CSH1
CSH2
CTAG1A
CTAG1B
CYB5R1
DEFA6
DEXI
DMKN
ECM1
EFEMP2
EMCN
ERP29
ETNK1
EVA1A
FBN1
FGF21
FZD7
GALNT11
GGH
GIP
GPX7
GYPA
HSP90B1
HSPA13
IL6R
IL6ST
ITPRIP
ITPRIPL1
KCNE5
KRT1
LAMP3
LAT
LCN2
LHB
LMO2
MYDGF
NAXD
NME3
OSMR
PAGE3
PDIA6
PGRMC1
PODXL
PPIB
PPIC
PRAP1
PRB1
PRB3
PRB4
PRR4
PSORS1C2
RAI2
RCN1
RNASE10
RNF144A
RNF144B
RNF170
SDC4
SDF2L1
SELENOM
SERPINE1
SERPINF1
SERPINI2
SGCA
SGTA
SHISA5
SIL1
SLPI
SOD3
SPINK4
SPP1
SRGN
SYT11
SYT4
TFF1
TMEM108
TMEM123
TMPO
TMUB1
TNFRSF19
TNFSF13
TXNDC12
UBL4A
UPK3A
VEGFC
VWC2
WFDC12
ZG16
ZG16B
61 interacting genes:
ALDH7A1
ALKBH4
ASB10
ASPH
BEX2
BMF
C20orf85
CAMLG
CCNC
CDSN
CHIC2
CLMP
CTDSP2
EHHADH
FAAP20
FAM25A
FAM25C
FAM25G
HDDC2
HGF
LAIR2
LNPEP
LRP2
LY96
MAGED4B
MMP2
MMP9
MSRB3
MYDGF
NDUFB2
NEIL2
ODAPH
P4HB
PDIA4
PELI1
PICK1
PIN1
POLL
POU4F2
PRKAA2
PTRH1
RAMP2
SCNM1
SEC61G
SGTA
SGTB
TBC1D21
TRAPPC2L
TRH
TRIAP1
TRIM32
TSG101
TTC23
TXN2
UBASH3A
UBE2F
UBQLN1
UBQLN2
VEZF1
XRN2
ZBED1
Entrez ID
54557
3934
HPRD ID
18049
02551
Ensembl ID
ENSG00000197860
ENSG00000148346
Uniprot IDs
Q96EQ0
P80188
PDB IDs
1DFV
1L6M
1NGL
1QQS
1X71
1X89
1X8U
3BY0
3CBC
3CMP
3DSZ
3DTQ
3FW4
3FW5
3HWD
3HWE
3HWF
3HWG
3I0A
3K3L
3PEC
3PED
3T1D
3TF6
3TZS
3U0D
4GH7
4IAW
4IAX
4K19
4MVI
4MVK
4MVL
4QAE
4ZFX
4ZHC
4ZHD
4ZHF
4ZHG
4ZHH
5JR8
5KHP
5KIC
5KID
5MHH
5N47
5N48
5NKN
6GQZ
6GR0
6O5D
6QMU
6S8V
6SUA
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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