SGTB and HSPA13

Data Source:
BioGRID (two hybrid)

		SGTB	HSPA13
Description		small glutamine rich tetratricopeptide repeat co-chaperone beta	heat shock protein family A (Hsp70) member 13
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane TRC Complex	Cytoplasm Mitochondrion Endoplasmic Reticulum Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Protein Binding Molecular Adaptor Activity	Protein Binding ATP Binding ATPase Activity Heat Shock Protein Binding Protein Folding Chaperone Unfolded Protein Binding Misfolded Protein Binding
	Biological Process	Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Ubiquitin-dependent ERAD Pathway Positive Regulation Of Chaperone-mediated Protein Folding	Cellular Response To Unfolded Protein Protein Refolding Chaperone Cofactor-dependent Protein Refolding
Pathways			Regulation of HSF1-mediated heat shock response
Drugs			Copper
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		116 interacting genes: ABCG4 ADAT2 ADIPOQ AGR2 AGR3 ASPH BTC C1QA C1QL4 C1QTNF5 C1QTNF6 C5orf46 CALR CCL3L3 CD200R1 CD3D CD68 CD79B CD99L2 CDH15 CDSN CMPK1 COL10A1 COL1A2 COLQ COMP CREB3L3 CSH1 CSH2 CTAG1A CTAG1B CYB5R1 DEFA6 DEXI DMKN ECM1 EFEMP2 EMCN ERP29 ETNK1 EVA1A FBN1 FGF21 FZD7 GALNT11 GGH GIP GPX7 GYPA HSP90B1 HSPA13 IL6R IL6ST ITPRIP ITPRIPL1 KCNE5 KRT1 LAMP3 LAT LCN2 LHB LMO2 MYDGF NAXD NME3 OSMR PAGE3 PDIA6 PGRMC1 PODXL PPIB PPIC PRAP1 PRB1 PRB3 PRB4 PRR4 PSORS1C2 RAI2 RCN1 RNASE10 RNF144A RNF144B RNF170 SDC4 SDF2L1 SELENOM SERPINE1 SERPINF1 SERPINI2 SGCA SGTA SHISA5 SIL1 SLPI SOD3 SPINK4 SPP1 SRGN SYT11 SYT4 TFF1 TMEM108 TMEM123 TMPO TMUB1 TNFRSF19 TNFSF13 TXNDC12 UBL4A UPK3A VEGFC VWC2 WFDC12 ZG16 ZG16B	10 interacting genes: BAG6 CRYGA POLE4 RMI1 SGTA SGTB SSR1 UBQLN1 UBQLN2 UBQLN4
Entrez ID		54557	6782
HPRD ID		18049	03061
Ensembl ID		ENSG00000197860	ENSG00000155304
Uniprot IDs		Q96EQ0	A0A140VK72 P48723
PDB IDs
Enriched GO Terms of Interacting Partners?
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