SGTB and LAMP3

Data Source:
BioGRID (two hybrid)

		SGTB	LAMP3
Description		small glutamine rich tetratricopeptide repeat co-chaperone beta	lysosomal associated membrane protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Membrane TRC Complex	Lysosomal Membrane Early Endosome Plasma Membrane Integral Component Of Membrane Late Endosome Membrane Vesicle Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Alveolar Lamellar Body Membrane
	Molecular Function	Protein Binding Molecular Adaptor Activity
	Biological Process	Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Ubiquitin-dependent ERAD Pathway Positive Regulation Of Chaperone-mediated Protein Folding	Adaptive Immune Response Regulation Of Autophagy Positive Regulation Of Gene Expression Response To Interferon-alpha Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Viral Entry Into Host Cell Establishment Of Protein Localization To Organelle Negative Regulation Of Proteasomal Protein Catabolic Process Regulation Of Viral Life Cycle
Pathways
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Age-related cognitive decline (memory) (slope of z-scores) ( 30954325) Parkinson's disease ( 21292315 28011712 21738487) Subjective response to lithium treatment ( 26503763)
Interacting Genes		116 interacting genes: ABCG4 ADAT2 ADIPOQ AGR2 AGR3 ASPH BTC C1QA C1QL4 C1QTNF5 C1QTNF6 C5orf46 CALR CCL3L3 CD200R1 CD3D CD68 CD79B CD99L2 CDH15 CDSN CMPK1 COL10A1 COL1A2 COLQ COMP CREB3L3 CSH1 CSH2 CTAG1A CTAG1B CYB5R1 DEFA6 DEXI DMKN ECM1 EFEMP2 EMCN ERP29 ETNK1 EVA1A FBN1 FGF21 FZD7 GALNT11 GGH GIP GPX7 GYPA HSP90B1 HSPA13 IL6R IL6ST ITPRIP ITPRIPL1 KCNE5 KRT1 LAMP3 LAT LCN2 LHB LMO2 MYDGF NAXD NME3 OSMR PAGE3 PDIA6 PGRMC1 PODXL PPIB PPIC PRAP1 PRB1 PRB3 PRB4 PRR4 PSORS1C2 RAI2 RCN1 RNASE10 RNF144A RNF144B RNF170 SDC4 SDF2L1 SELENOM SERPINE1 SERPINF1 SERPINI2 SGCA SGTA SHISA5 SIL1 SLPI SOD3 SPINK4 SPP1 SRGN SYT11 SYT4 TFF1 TMEM108 TMEM123 TMPO TMUB1 TNFRSF19 TNFSF13 TXNDC12 UBL4A UPK3A VEGFC VWC2 WFDC12 ZG16 ZG16B	1 interacting genes: SGTB
Entrez ID		54557	27074
HPRD ID		18049	12062
Ensembl ID		ENSG00000197860	ENSG00000078081
Uniprot IDs		Q96EQ0	Q9UQV4
PDB IDs			4AKM
Enriched GO Terms of Interacting Partners?
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