PRELP and FBLN2

Data Source:
HPRD (in vitro)

		PRELP	FBLN2
Description		proline and arginine rich end leucine rich repeat protein	fibulin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Golgi Lumen Extracellular Matrix Lysosomal Lumen Collagen-containing Extracellular Matrix Extracellular Exosome Extracellular Vesicle	Extracellular Region Extracellular Matrix Collagen-containing Extracellular Matrix Extracellular Vesicle
	Molecular Function	Extracellular Matrix Structural Constituent Heparin Binding Extracellular Matrix Structural Constituent Conferring Compression Resistance	Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding Extracellular Matrix Constituent Conferring Elasticity Extracellular Matrix Binding
	Biological Process	Skeletal System Development Cell Aging Keratan Sulfate Biosynthetic Process Keratan Sulfate Catabolic Process	Positive Regulation Of Cell-substrate Adhesion Extracellular Matrix Organization
Pathways		Keratan sulfate biosynthesis Keratan sulfate degradation Defective CHST6 causes MCDC1 Defective ST3GAL3 causes MCT12 and EIEE15 Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)	Molecules associated with elastic fibres Molecules associated with elastic fibres
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder (inattention symptoms) ( 32595297) Blood protein levels ( 29875488)	Bipolar disorder with mood-incongruent psychosis ( 23092984) Body mass index ( 26426971) Response to cognitive-behavioural therapy in anxiety disorder ( 26989097)
Interacting Genes		6 interacting genes: COL1A1 COL2A1 FBLN2 FN1 HSPG2 NID1	30 interacting genes: ACAN ATN1 BCAN COL18A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 COL8A1 ELN ERCC6 FBN1 FBXW5 FN1 HSD3B7 HSPG2 ITGB3 JOSD1 LAMA1 LAMA5 LAMC2 LCE3D NID1 OTX1 PRELP VCAN ZNF408 ZNF414
Entrez ID		5549	2199
HPRD ID		03556	00630
Ensembl ID		ENSG00000188783	ENSG00000163520
Uniprot IDs		P51888	P98095 Q86V58 Q9Y3V7
PDB IDs
Enriched GO Terms of Interacting Partners?
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