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FBLN2 and BCAN
Data Source:
HPRD
(in vitro)
FBLN2
BCAN
Description
fibulin 2
brevican
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Matrix
Collagen-containing Extracellular Matrix
Extracellular Vesicle
Extracellular Region
Golgi Lumen
Extracellular Matrix
Anchored Component Of Membrane
Lysosomal Lumen
Glutamatergic Synapse
Molecular Function
Extracellular Matrix Structural Constituent
Calcium Ion Binding
Protein Binding
Extracellular Matrix Constituent Conferring Elasticity
Extracellular Matrix Binding
Protein Binding
Hyaluronic Acid Binding
Carbohydrate Binding
Biological Process
Positive Regulation Of Cell-substrate Adhesion
Extracellular Matrix Organization
Skeletal System Development
Cell Adhesion
Central Nervous System Development
Hippocampus Development
Extracellular Matrix Organization
Chondroitin Sulfate Biosynthetic Process
Chondroitin Sulfate Catabolic Process
Dermatan Sulfate Biosynthetic Process
Synapse Maturation
Pathways
Molecules associated with elastic fibres
Molecules associated with elastic fibres
Degradation of the extracellular matrix
A tetrasaccharide linker sequence is required for GAG synthesis
Chondroitin sulfate biosynthesis
Dermatan sulfate biosynthesis
CS/DS degradation
ECM proteoglycans
Defective B4GALT7 causes EDS, progeroid type
Defective B3GAT3 causes JDSSDHD
Defective CHST3 causes SEDCJD
Defective CHST14 causes EDS, musculocontractural type
Defective CHSY1 causes TPBS
Defective B3GALT6 causes EDSP2 and SEMDJL1
Drugs
Diseases
GWAS
Bipolar disorder with mood-incongruent psychosis (
23092984
)
Body mass index (
26426971
)
Response to cognitive-behavioural therapy in anxiety disorder (
26989097
)
Blood protein levels (
30072576
29875488
)
Interacting Genes
30 interacting genes:
ACAN
ATN1
BCAN
COL18A1
COL4A1
COL4A2
COL4A3
COL4A4
COL4A5
COL4A6
COL8A1
ELN
ERCC6
FBN1
FBXW5
FN1
HSD3B7
HSPG2
ITGB3
JOSD1
LAMA1
LAMA5
LAMC2
LCE3D
NID1
OTX1
PRELP
VCAN
ZNF408
ZNF414
10 interacting genes:
ADAMTS4
FBLN2
MMP1
MMP10
MMP13
MMP2
MMP3
MMP7
MMP8
TNR
Entrez ID
2199
63827
HPRD ID
00630
02644
Ensembl ID
ENSG00000163520
ENSG00000132692
Uniprot IDs
P98095
Q86V58
Q9Y3V7
Q96GW7
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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