PRELP and NID1

Data Source:
HPRD (in vitro)

		PRELP	NID1
Description		proline and arginine rich end leucine rich repeat protein	nidogen 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Golgi Lumen Extracellular Matrix Lysosomal Lumen Collagen-containing Extracellular Matrix Extracellular Exosome Extracellular Vesicle	Extracellular Region Basement Membrane Plasma Membrane Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Extracellular Matrix Structural Constituent Heparin Binding Extracellular Matrix Structural Constituent Conferring Compression Resistance	Extracellular Matrix Structural Constituent Calcium Ion Binding Collagen Binding Laminin Binding Laminin-1 Binding Proteoglycan Binding
	Biological Process	Skeletal System Development Cell Aging Keratan Sulfate Biosynthetic Process Keratan Sulfate Catabolic Process	Cell-matrix Adhesion Positive Regulation Of Cell-substrate Adhesion Extracellular Matrix Organization Glomerular Basement Membrane Development Basement Membrane Organization
Pathways		Keratan sulfate biosynthesis Keratan sulfate degradation Defective CHST6 causes MCDC1 Defective ST3GAL3 causes MCT12 and EIEE15 Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)	Degradation of the extracellular matrix Degradation of the extracellular matrix Laminin interactions Laminin interactions
Drugs			Urokinase
Diseases
GWAS		Attention deficit hyperactivity disorder (inattention symptoms) ( 32595297) Blood protein levels ( 29875488)	Cutaneous nevi ( 21478494) Diverticulitis ( 28585551) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Mean platelet volume ( 32888494) Response to levetiracetam in genetic generalized epilepsy ( 32308125) Urate levels in overweight individuals ( 25811787)
Interacting Genes		6 interacting genes: COL1A1 COL2A1 FBLN2 FN1 HSPG2 NID1	21 interacting genes: APP COL13A1 COL1A1 COL4A1 FBLN1 FBLN2 FGA FGB HSPG2 ITGAV ITGB3 LACRT LAMA1 LAMC1 LAMC2 LGALS3BP PLAU PLXDC1 PRELP PTPRF SKIL
Entrez ID		5549	4811
HPRD ID		03556	00574
Ensembl ID		ENSG00000188783	ENSG00000116962
Uniprot IDs		P51888	P14543
PDB IDs			1NDX
Enriched GO Terms of Interacting Partners?
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