STRADB and NEB

Data Source:
BioGRID (two hybrid)

		STRADB	NEB
Description		STE20 related adaptor beta	nebulin
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Aggresome	Cytosol Actin Cytoskeleton Z Disc Extracellular Exosome
	Molecular Function	Protein Kinase Activity Protein Binding ATP Binding	Protein Binding Structural Constituent Of Muscle Actin Filament Binding
	Biological Process	Cell Morphogenesis Protein Phosphorylation Protein Export From Nucleus Cell Cycle Arrest JNK Cascade Activation Of Protein Kinase Activity Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand	Muscle Organ Development Somatic Muscle Development Muscle Filament Sliding Regulation Of Actin Filament Length Muscle Fiber Development Cardiac Muscle Thin Filament Assembly
Pathways		Energy dependent regulation of mTOR by LKB1-AMPK	Striated Muscle Contraction
Drugs
Diseases			Distal muscular dystrophies, including: Welander distal myopathy (WDM); Tibial muscular dystrophy (TMD); Nonaka distal myopathy with rimmed vacuoles (DMRV); Miyoshi myopathy (MM); Laing myopathy (MPD1); Distal nebulin myopathy (DNM); Distal desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Distal myotilinopathy (MFM3); Distal zaspopathy (MFM4); Distal myopathy 3 (MPD2, VCPDM) Nemaline myopathy
GWAS			Asparaginase-induced acute pancreatitis in acute lymphoblastic leukemia (onset time) ( 27114598) Creatine kinase levels ( 29403010) Estimated glomerular filtration rate ( 31152163 31451708) Letter-number span reordering ( 31596458) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Rapid automised naming of letters ( 30741946) Response to cognitive-behavioural therapy in anxiety disorder ( 26989097) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		7 interacting genes: CAB39 GRB2 MAP3K7 NEB STK11 TRAF6 XIAP	24 interacting genes: ABI1 ACO1 ACTG2 ACTN4 AKTIP APC CALM1 DES ENO3 LIMS1 MTDH MYOM2 MYPN PTPN11 STRADB TMOD1 TMOD4 TPM1 TPM2 TRIM55 TRIM63 TTN XIRP1 XIRP2
Entrez ID		55437	4703
HPRD ID		09546	01196
Ensembl ID		ENSG00000082146	ENSG00000183091
Uniprot IDs		Q9C0K7	P20929 Q05C45 Q96MF8
PDB IDs			1ARK 1NEB
Enriched GO Terms of Interacting Partners?
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