SETD5 and PLEKHG4

Data Source:
BioGRID (two hybrid)

		SETD5	PLEKHG4
Description		SET domain containing 5	pleckstrin homology and RhoGEF domain containing G4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Euchromatin Nucleus Nucleoplasm Cdc73/Paf1 Complex
	Molecular Function	Histone Methyltransferase Activity (H3-K9 Specific) Histone Methyltransferase Activity (H3-K36 Specific)	Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Covalent Chromatin Modification Regulation Of DNA-templated Transcription, Elongation Regulation Of Histone Acetylation Cognition Histone H3-K9 Methylation Regulation Of Synapse Assembly Histone H3-K36 Trimethylation Regulation Of Chromatin Organization	Regulation Of Catalytic Activity
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Attention deficit hyperactivity disorder (inattention symptoms) ( 32595297) Bitter alcoholic beverage consumption ( 31046077) Cerebrospinal fluid clusterin levels ( 26545630) Glucose homeostasis traits ( 25524916)	Blood protein levels ( 29875488 28240269) Heel bone mineral density ( 28869591) Refractive error ( 32231278)
Interacting Genes		11 interacting genes: CALCOCO2 CCDC85B CEP70 DPPA2 KRT40 LDOC1 MTUS2 PLEKHG4 SORBS3 TP53BP2 TRAF2	65 interacting genes: A1CF ARHGEF5 ARMC7 BEX2 CCDC120 CCDC187 CDC42 CDKN2C CHIC2 COIL DCUN1D5 DPPA3 DTX2 DUSP13 FAM161A FGD2 GATA3 GCM2 GSTZ1 HCK HOXB9 HOXC8 KRT3 KRT75 MALSU1 MATR3 MDFI METAP1 MSRB3 MTA1 MYEF2 MYOZ1 NATD1 OTX1 PFKFB1 PKP2 PPP1R32 PRPF18 PRPF31 PSMB1 RHOA RIN1 SAXO1 SETD5 SH2D4A SHISA6 SIX1 SMCP SMG9 TBC1D22B TBX18 TEKT3 TENT5D TFAP2D TFG TRIM55 TRIM63 TSSK3 TTC23 USP2 VPS37C ZCCHC14 ZNF148 ZNF319 ZNF648
Entrez ID		55209	25894
HPRD ID		13338	10890
Ensembl ID		ENSG00000168137	ENSG00000196155
Uniprot IDs		E7EWN3 Q9C0A6	A0A024R6X4 Q58EX7
PDB IDs
Enriched GO Terms of Interacting Partners?
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