PIWIL2 and DDX4

Data Source:
HPRD (in vitro, in vivo)

		PIWIL2	DDX4
Description		piwi like RNA-mediated gene silencing 2	DEAD-box helicase 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Perinucleolar Chromocenter Chromatoid Body P Granule Pi-body Dense Body PET Complex	Nucleus Cytoplasm P Granule Perinuclear Region Of Cytoplasm Pi-body PiP-body
	Molecular Function	MRNA Binding Endoribonuclease Activity Protein Binding PiRNA Binding Metal Ion Binding Polysome Binding	RNA Binding RNA Helicase Activity ATP Binding ATPase Activity
	Biological Process	RNA 5'-end Processing Multicellular Organism Development Spermatogenesis Negative Regulation Of Transposition Germ-line Stem Cell Population Maintenance Gene Silencing By RNA PiRNA Metabolic Process Negative Regulation Of Circadian Rhythm DNA Methylation Involved In Gamete Generation Positive Regulation Of Translation Oogenesis Rhythmic Process Meiotic Cell Cycle Positive Regulation Of Meiosis I Positive Regulation Of Histone H3-K14 Acetylation RNA Phosphodiester Bond Hydrolysis, Endonucleolytic PiRNA Biosynthetic Process Positive Regulation Of Histone H3-K9 Acetylation	Male Meiotic Nuclear Division Male Meiosis I Multicellular Organism Development Gamete Generation Spermatogenesis Negative Regulation Of Transposition Cell Differentiation Flagellated Sperm Motility Gene Silencing By RNA PiRNA Metabolic Process DNA Methylation Involved In Gamete Generation PiRNA Biosynthetic Process
Pathways		PIWI-interacting RNA (piRNA) biogenesis	PIWI-interacting RNA (piRNA) biogenesis
Drugs
Diseases
GWAS		Hypertriglyceridemia ( 23505323)	Cocaine dependence ( 31212010)
Interacting Genes		3 interacting genes: DDX4 DICER1 TBCB	5 interacting genes: PIWIL2 RANBP9 SPSB1 SPSB2 SPSB4
Entrez ID		55124	54514
HPRD ID		11434	05593
Ensembl ID		ENSG00000197181	ENSG00000152670
Uniprot IDs		Q8TC59 W0HK13	Q9NQI0
PDB IDs		3O7X 3QIR
Enriched GO Terms of Interacting Partners?
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