PLEKHJ1 and PPBP

Data Source:
BioGRID (two hybrid)

		PLEKHJ1	PPBP
Description		pleckstrin homology domain containing J1	pro-platelet basic protein
Image		No pdb structure
GO Annotations	Cellular Component	Early Endosome Trans-Golgi Network Cytosol Recycling Endosome	Extracellular Region Extracellular Space Platelet Alpha Granule Lumen Tertiary Granule Lumen
	Molecular Function	Protein Binding	Glucose Transmembrane Transporter Activity Protein Binding Chemokine Activity Growth Factor Activity CXCR Chemokine Receptor Binding
	Biological Process	Receptor Recycling Endosome Organization Retrograde Transport, Endosome To Golgi	Platelet Degranulation Inflammatory Response G Protein-coupled Receptor Signaling Pathway Neutrophil Chemotaxis Defense Response To Bacterium Neutrophil Degranulation Positive Regulation Of Cell Division Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Cellular Response To Lipopolysaccharide Glucose Transmembrane Transport
Pathways			Platelet degranulation Chemokine receptors bind chemokines G alpha (i) signalling events Neutrophil degranulation
Drugs			Ethanesulfonic acid Copper
Diseases
GWAS		Pulse pressure ( 26390057)	Metabolite levels ( 22916037)
Interacting Genes		11 interacting genes: ACVR1 APP DNMT3B IKBKG LAGE3 NTAQ1 PHETA1 PHETA2 PIH1D2 PPBP TGFBR1	32 interacting genes: CCL13 CCL21 CCL26 CCL28 CCL5 CCL8 CELF1 CMTM6 COPG1 COPS7A COX17 CTSG CXCL10 CXCL11 CXCL12 CXCL14 CXCL6 CXCL9 CXCR1 CXCR2 DMWD EFNA1 MAPK6 MOB3B NDUFB11 NR4A1 PLEKHJ1 PMAIP1 RAB10 RPS27 SCFD1 STRN4
Entrez ID		55111	5473
HPRD ID		15150	07171
Ensembl ID		ENSG00000104886	ENSG00000163736
Uniprot IDs		K7EIZ3 Q9NW61	P02775
PDB IDs			1F9P 1NAP 1TVX
Enriched GO Terms of Interacting Partners?
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