RNF31 and ATN1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RNF31	ATN1
Description		ring finger protein 31	atrophin 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoplasmic Side Of Plasma Membrane CD40 Receptor Complex LUBAC Complex	Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Cell Junction Perinuclear Region Of Cytoplasm
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Ubiquitin Binding Metal Ion Binding	RNA Polymerase II Transcription Factor Binding Transcription Corepressor Activity Protein Binding Protein Domain Specific Binding
	Biological Process	Protein Polyubiquitination I-kappaB Kinase/NF-kappaB Signaling Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway CD40 Signaling Pathway Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling T Cell Receptor Signaling Pathway Positive Regulation Of NF-kappaB Transcription Factor Activity Protein Linear Polyubiquitination Positive Regulation Of Protein Targeting To Mitochondrion	Negative Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Neuron Apoptotic Process
Pathways		Regulation of TNFR1 signaling TNFR1-induced NFkappaB signaling pathway	Regulation of PTEN gene transcription
Drugs
Diseases			Dentatorubropallidoluysian atrophy (DRPLA)
GWAS		Suicide behavior ( 26079190)	Refractive error ( 32231278)
Interacting Genes		46 interacting genes: ATN1 ATXN1 ATXN7 AZI2 CCDC24 CDC34 GFI1B HDAC6 KIF1A KRTAP9-2 NOS3 NR0B1 NR0B2 PITX1 PRKCA RBCK1 SEPTIN2 SMAD3 SNRPC SOCS3 SPATA2 STK4 TLE5 TRAF1 TRAF6 TRIM25 TSSC4 UBC UBE2C UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2K UBE2L3 UBE2O UBE2Q1 UBE2Q2 UBE2R2 UBE2T UBE2W VASN VDAC1	121 interacting genes: AGRN ALG13 ARF3 ATRX BAG3 BAG6 BAIAP2 CACNB1 CASP1 CASP3 CBFA2T2 CENPJ CHRD CRACR2A CRIP2 CSNK2A1 CTNND2 DGCR6L DMPK DMRT3 DVL1 DVL2 ECM1 EFEMP1 EFEMP2 ETNK2 EWSR1 FBLN1 FBLN2 FBLN5 GAPDH GCC1 GIGYF1 GRN HGS HINFP HNRNPF HSPG2 ITCH JAG2 KAT6A KAT6B KAT7 KRT31 KRTAP12-2 KRTAP15-1 KRTAP19-2 KRTAP19-5 KRTAP4-12 KRTAP6-2 KRTAP9-3 LENG8 LRP2 LTBP1 LTBP4 LYST MAGI1 MAGI2 MAP7D1 MBP MDFI MEGF11 MEGF6 MEGF8 NCK2 NELL1 NELL2 NOC2L NR2E1 OLIG3 P4HA3 PCSK5 PDCD6IP PFKL PIN1 PITX1 PITX2 PLSCR1 PPP1R32 PRRC2A PRRC2B PSMA3 PSME3 RAD54L2 RBFOX1 RBFOX2 RBM10 RBM14 RBM4B RBPMS RCHY1 RERE RHOXF2 RNF115 RNF31 RUNX1T1 SH3RF1 SIAH1 SIAH2 SLC25A48 SLIT1 SPAG5 SS18L1 SSPOP STXBP4 SYVN1 TEKT3 TEP1 TLE1 TLE5 TNFAIP8 TRIP6 USP2 USP54 VIM WDR5 WWP1 WWP2 ZMYND8 ZNF503 ZSWIM8
Entrez ID		55072	1822
HPRD ID		11516	06311
Ensembl ID		ENSG00000092098	ENSG00000111676
Uniprot IDs		Q96EP0	P54259 Q86V38
PDB IDs		2CT7 4DBG 4JUY 4LJO 4LJP 4LJQ 4OWF 4OYJ 4OYK 4P09 4P0A 4P0B 5EDV 5LJN 5X0W 6GZY 6KC5 6KC6 6SC5 6SC6 6SC7 6SC8 6SC9
Enriched GO Terms of Interacting Partners?
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