RNF31 and UBE2Q1

Data Source:
BioGRID (pull down)

		RNF31	UBE2Q1
Description		ring finger protein 31	ubiquitin conjugating enzyme E2 Q1
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GO Annotations	Cellular Component	Cytosol Cytoplasmic Side Of Plasma Membrane CD40 Receptor Complex LUBAC Complex	Nucleus Cytosol Filopodium
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Ubiquitin Binding Metal Ion Binding	Protein Binding ATP Binding Ubiquitin Conjugating Enzyme Activity
	Biological Process	Protein Polyubiquitination I-kappaB Kinase/NF-kappaB Signaling Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway CD40 Signaling Pathway Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling T Cell Receptor Signaling Pathway Positive Regulation Of NF-kappaB Transcription Factor Activity Protein Linear Polyubiquitination Positive Regulation Of Protein Targeting To Mitochondrion	Protein Polyubiquitination Suckling Behavior Embryo Implantation Mating Behavior Fertilization Reproductive System Development Prolactin Secretion
Pathways		Regulation of TNFR1 signaling TNFR1-induced NFkappaB signaling pathway	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Suicide behavior ( 26079190)	Cerebrospinal fluid levels of Alzheimer's disease-related proteins ( 25340798)
Interacting Genes		46 interacting genes: ATN1 ATXN1 ATXN7 AZI2 CCDC24 CDC34 GFI1B HDAC6 KIF1A KRTAP9-2 NOS3 NR0B1 NR0B2 PITX1 PRKCA RBCK1 SEPTIN2 SMAD3 SNRPC SOCS3 SPATA2 STK4 TLE5 TRAF1 TRAF6 TRIM25 TSSC4 UBC UBE2C UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2K UBE2L3 UBE2O UBE2Q1 UBE2Q2 UBE2R2 UBE2T UBE2W VASN VDAC1	12 interacting genes: ECPAS FHL3 IRF2BPL ITCH LMNA MDM2 RNF26 RNF31 RNF7 STUB1 TP53 UBC
Entrez ID		55072	55585
HPRD ID		11516	15601
Ensembl ID		ENSG00000092098	ENSG00000160714
Uniprot IDs		Q96EP0	Q7Z7E8
PDB IDs		2CT7 4DBG 4JUY 4LJO 4LJP 4LJQ 4OWF 4OYJ 4OYK 4P09 4P0A 4P0B 5EDV 5LJN 5X0W 6GZY 6KC5 6KC6 6SC5 6SC6 6SC7 6SC8 6SC9	2QGX
Enriched GO Terms of Interacting Partners?
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