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ATN1 and SYVN1
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
ATN1
SYVN1
Description
atrophin 1
synoviolin 1
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Nuclear Matrix
Cell Junction
Perinuclear Region Of Cytoplasm
Hrd1p Ubiquitin Ligase Complex
Hrd1p Ubiquitin Ligase ERAD-L Complex
Nucleoplasm
Cytoplasm
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Smooth Endoplasmic Reticulum
Membrane
Integral Component Of Endoplasmic Reticulum Membrane
Derlin-1 Retrotranslocation Complex
Endoplasmic Reticulum Quality Control Compartment
Molecular Function
RNA Polymerase II Transcription Factor Binding
Transcription Corepressor Activity
Protein Binding
Protein Domain Specific Binding
Protein Binding
Metal Ion Binding
Unfolded Protein Binding
Chaperone Binding
ATPase Binding
Ubiquitin Protein Ligase Activity
Ubiquitin-specific Protease Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Central Nervous System Development
Neuron Apoptotic Process
Immature B Cell Differentiation
Ubiquitin-dependent Protein Catabolic Process
Protein Ubiquitination
Ubiquitin-dependent ERAD Pathway
Retrograde Protein Transport, ER To Cytosol
IRE1-mediated Unfolded Protein Response
ERAD Pathway
Protein Stabilization
Protein K48-linked Ubiquitination
Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Endoplasmic Reticulum Mannose Trimming
Pathways
Regulation of PTEN gene transcription
XBP1(S) activates chaperone genes
Hedgehog ligand biogenesis
Hh mutants are degraded by ERAD
ER Quality Control Compartment (ERQC)
Drugs
Diseases
Dentatorubropallidoluysian atrophy (DRPLA)
GWAS
Refractive error (
32231278
)
Blood protein levels (
28240269
)
Crohn's disease (
32581322
)
Interacting Genes
121 interacting genes:
AGRN
ALG13
ARF3
ATRX
BAG3
BAG6
BAIAP2
CACNB1
CASP1
CASP3
CBFA2T2
CENPJ
CHRD
CRACR2A
CRIP2
CSNK2A1
CTNND2
DGCR6L
DMPK
DMRT3
DVL1
DVL2
ECM1
EFEMP1
EFEMP2
ETNK2
EWSR1
FBLN1
FBLN2
FBLN5
GAPDH
GCC1
GIGYF1
GRN
HGS
HINFP
HNRNPF
HSPG2
ITCH
JAG2
KAT6A
KAT6B
KAT7
KRT31
KRTAP12-2
KRTAP15-1
KRTAP19-2
KRTAP19-5
KRTAP4-12
KRTAP6-2
KRTAP9-3
LENG8
LRP2
LTBP1
LTBP4
LYST
MAGI1
MAGI2
MAP7D1
MBP
MDFI
MEGF11
MEGF6
MEGF8
NCK2
NELL1
NELL2
NOC2L
NR2E1
OLIG3
P4HA3
PCSK5
PDCD6IP
PFKL
PIN1
PITX1
PITX2
PLSCR1
PPP1R32
PRRC2A
PRRC2B
PSMA3
PSME3
RAD54L2
RBFOX1
RBFOX2
RBM10
RBM14
RBM4B
RBPMS
RCHY1
RERE
RHOXF2
RNF115
RNF31
RUNX1T1
SH3RF1
SIAH1
SIAH2
SLC25A48
SLIT1
SPAG5
SS18L1
SSPOP
STXBP4
SYVN1
TEKT3
TEP1
TLE1
TLE5
TNFAIP8
TRIP6
USP2
USP54
VIM
WDR5
WWP1
WWP2
ZMYND8
ZNF503
ZSWIM8
13 interacting genes:
APP
ATN1
CLU
ERN1
GPR37
TP53
UBE2D2
UBE2D3
UBE2G1
UBE2U
UBE2Z
USP15
USP7
Entrez ID
1822
84447
HPRD ID
06311
07618
Ensembl ID
ENSG00000111676
ENSG00000162298
Uniprot IDs
P54259
Q86V38
Q86TM6
PDB IDs
6A3Z
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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