PPP1R3C and EPM2A

Data Source:
BioGRID (two hybrid)

		PPP1R3C	EPM2A
Description		protein phosphatase 1 regulatory subunit 3C	EPM2A glucan phosphatase, laforin
Image		No pdb structure
GO Annotations	Cellular Component	Protein Phosphatase Type 1 Complex Cytosol	Nucleus
	Molecular Function	Protein Serine/threonine Phosphatase Activity Protein Binding Protein Phosphatase 1 Binding Protein Phosphatase Binding Glycogen Binding	Protein Binding
	Biological Process	Glycogen Metabolic Process Glycogen Biosynthetic Process Regulation Of Glycogen Biosynthetic Process Protein Dephosphorylation	Positive Regulation Of Macroautophagy Negative Regulation Of TOR Signaling
Pathways		Glycogen synthesis Myoclonic epilepsy of Lafora	Glycogen synthesis Myoclonic epilepsy of Lafora
Drugs
Diseases			Progressive myoclonic epilepsy (PME), including: Lafora disease (LBD); Unverricht-Lundborg disease (ULD); Neuronal ceroid lipofuscinoses (NCL); Type I sialidosis; Action myoclonus-renal failure syndrome (AMRF); Type III Gaucher disease (GD)
GWAS			Loneliness (multivariate analysis) ( 27629369) Mean platelet volume ( 32888494 27863252) Methadone dose in opioid dependence ( 28115739) Response to mepolizumab in severe asthma ( 29229094)
Interacting Genes		9 interacting genes: APP EPM2A LONRF1 LXN NHLRC1 PPP1CA PPP1CB PPP1CC SGTA	16 interacting genes: COX5A EIF2B1 EPM2AIP1 HMGXB4 NFU1 NHLRC1 PKM PPP1R3C PPP1R3D PRKAA1 PRKAA2 PRKAB2 PSMC3 SRPK2 TDG TOPORS
Entrez ID		5507	7957
HPRD ID		04298	06345
Ensembl ID		ENSG00000119938	ENSG00000112425
Uniprot IDs		Q9UQK1	H0UI04 O95278
PDB IDs			4R30 4RKK
Enriched GO Terms of Interacting Partners?
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